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Lebrikizumab information


Lebrikizumab
Monoclonal antibody
TypeWhole antibody
SourceHumanized
TargetIL-13
Clinical data
Other namesMILR1444A, RG3637, TNX-650
Routes of
administration
Subcutaneous
ATC code
  • D11AH10 (WHO)
Legal status
Legal status
  • EU: Rx-only[1][2]
Identifiers
CAS Number
  • 953400-68-5 ☒N
DrugBank
  • DB11914 checkY
ChemSpider
  • none
UNII
  • U9JLP7V031
KEGG
  • D09633 checkY
Chemical and physical data
FormulaC6434H9972N1700O2034S50
Molar mass145287.42 g·mol−1
 ☒NcheckY (what is this?)  (verify)

Lebrikizumab, sold under the brand name Ebglyss is a humanized monoclonal antibody used for the treatment of atopic dermatitis (atopic eczema).[1]

The most common side effects include injection site reactions, dry eye and conjunctivitis (redness and discomfort in the eye) including allergic conjunctivitis.[1]

It was approved for medical use in the European Union in November 2023.[1]

  1. ^ a b c d "Ebglyss EPAR". European Medicines Agency (EMA). 21 November 2023. Archived from the original on 22 November 2023. Retrieved 22 November 2023. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
  2. ^ "Ebglyss Product information". Union Register of medicinal products. 17 November 2023. Archived from the original on 26 November 2023. Retrieved 11 December 2023.

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