Latanoprost, sold under the brand name Xalatan among others, is a medication used to treat increased pressure inside the eye (intraocular pressure).[5] This includes ocular hypertension and open-angle glaucoma.[5] Latanaprost is applied as eye drops to the eyes.[5] Onset of effects is usually within four hours, and they last for up to a day.[5]
Common side effects include blurry vision, redness of the eye, itchiness, and darkening of the iris.[5] Latanoprost is in the prostaglandin analogue family of medications.[5] It works by increasing the outflow of aqueous fluid from the eyes through the uveoscleral tract.[6]
Latanoprost was approved for medical use in the United States and the European Union in 1996.[5][3] It is on the World Health Organization's List of Essential Medicines.[7] Latanoprost is available as a generic medication.[8] In 2021, it was the 68th most commonly prescribed medication in the United States with more than 9million prescriptions.[9][10] It is available as a combination with netarsudil and with timolol.
^"Latanoprost 50 micrograms/ml eye drops, solution - Summary of Product Characteristics (SmPC)". (emc). 1 July 2022. Archived from the original on 1 July 2022. Retrieved 1 July 2022.
^Cite error: The named reference Xalatan FDA label was invoked but never defined (see the help page).
^ ab"Catiolanze EPAR". European Medicines Agency (EMA). 14 September 2023. Archived from the original on 5 December 2023. Retrieved 11 December 2023.
^"Catiolanze Product information". Union Register of medicinal products. 16 November 2023. Retrieved 11 December 2023.
^ abcdefg"Latanoprost Monograph". The American Society of Health-System Pharmacists. Archived from the original on 28 December 2016. Retrieved 8 December 2016.
^Patel SS, Spencer CM (1996). "Latanoprost. A review of its pharmacological properties, clinical efficacy and tolerability in the management of primary open-angle glaucoma and ocular hypertension". Drugs Aging. 9 (5): 363–378. doi:10.2165/00002512-199609050-00007. PMID 8922563. S2CID 25169085.
^World Health Organization (2023). The selection and use of essential medicines 2023: web annex A: World Health Organization model list of essential medicines: 23rd list (2023). Geneva: World Health Organization. hdl:10665/371090. WHO/MHP/HPS/EML/2023.02.
^Hamilton R (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 413. ISBN 9781284057560.
^"The Top 300 of 2021". ClinCalc. Retrieved 14 January 2024.
^"Latanoprost - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
Latanoprost, sold under the brand name Xalatan among others, is a medication used to treat increased pressure inside the eye (intraocular pressure). This...
the ophthalmic solution latanoprost, the size of the palpebral fissure can be increased. The condition is reversible. Latanoprost is a prostaglandin F receptor...
those for men, although topical or systemic estrogen is used more often. Latanoprost and bimatoprost are specific PGF2a analogues applied topically, and have...
agonists: timolol and brimonidine with prostaglandin analogs: timolol and latanoprost timolol and travoprost Timolol is marketed under many trade names worldwide...
meshwork. This work led to the development of prodrugs of PGF2α, including latanoprost, an isopropyl analogue of PGF2α, approved by the FDA in 1996, bimatoprost...
is compared to intravenous use; by demonstration, the elimination of latanoprost acid from plasma is rapid (half-life 17 minutes) after either ophthalmic...
delivered via eye drop, as well as a fixed-dose combination (FDC) with latanoprost, one of the leading current treatments for OHT and POAG. "Clinical Development...
pressure (IOP) and at least as effective as the prostaglandin analogs latanoprost and travoprost in reducing IOP. Bimatoprost may be used to treat small...
deposition from blood products. Certain eyedrops – prostaglandin analogues (latanoprost, isopropyl unoprostone, travoprost, and bimatoprost) are used topically...
as selective receptor agonists of FP viz., cloprostenol, flupostenol, latanoprost, and tafluprost (acid form) have FP binding affinities and stimulating...
PGF2α. The following medications are analogues of prostaglandin F2α: Latanoprost Bimatoprost Travoprost Carboprost O'Neil MJ, ed. (2013). The Merck index:...
causation. The principal medication known to affect the retina are:- latanoprost, epinephrine, rosiglitazone, timolol and thiazolidinediones among others...
first-line treatment for glaucoma. Prostaglandin analogues, such as latanoprost, bimatoprost and travoprost, reduce the IOP by increasing the aqueous...
intraocular pressure. Other PGF2α analogues with the same mechanism include latanoprost and travoprost. Tafluprost, as a lipophilic ester, easily penetrates...
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