positive regulation of cell population proliferation
cytoskeleton organization
keratinization
cornification
negative regulation of cytolysis by symbiont of host cells
negative regulation of entry of bacterium into host cell
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
3853
16688
Ensembl
ENSG00000205420
ENSMUSG00000023041
UniProt
P02538
Q9Z331 Q3UV11
RefSeq (mRNA)
NM_005554
NM_010669
RefSeq (protein)
NP_005545
NP_034799
Location (UCSC)
Chr 12: 52.49 – 52.49 Mb
Chr 15: 101.58 – 101.59 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Keratin 6A is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence determined.[5] Analysis of the sequence of this keratin together with that of the first type I keratin led to the discovery of the four helical domains in the central rod of keratins.[5] In humans Keratin 6A is encoded by the KRT6A gene.[6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000205420 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000023041 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ abHanukoglu, I.; Fuchs, E. (Jul 1983). "The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins". Cell. 33 (3): 915–24. doi:10.1016/0092-8674(83)90034-X. PMID 6191871. S2CID 21490380.
^Rosenberg M, Fuchs E, Le Beau MM, Eddy RL, Shows TB (1991). "Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12". Cytogenet. Cell Genet. 57 (1): 33–8. doi:10.1159/000133109. PMID 1713141.
^Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
Keratin6A is one of the 27 different type II keratins expressed in humans. Keratin6A was the first type II keratin sequence determined. Analysis of the...
Keratin (/ˈkɛrətɪn/) is one of a family of structural fibrous proteins also known as scleroproteins. Alpha-keratin (α-keratin) is a type of keratin found...
Keratin, type II cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the...
of oral mucosa and esophagus. This keratin 6 isoform is thought be less abundant than the closely related keratin6A protein. Mutations in the gene encoding...
Keratin 14 is a member of the type I keratin family of intermediate filament proteins. Keratin 14 was the first type I keratin sequence determined. Keratin...
is encoded by the KRT19 gene. Keratin 19 is a type I keratin. Keratin 19 is a member of the keratin family. The keratins are intermediate filament proteins...
Cytokeratins are keratin proteins found in the intracytoplasmic cytoskeleton of epithelial tissue. They are an important component of intermediate filaments...
Keratin 2A also known as keratin 2E or keratin 2 is a protein that in humans is encoded by the KRT2A gene. Keratin 2A is a type II cytokeratin. It is found...
Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate...
antibodies that detect two markers of myoepithelial cells, cytokeratin 5 and keratin6A); 3) the presence of a thick fibrous capsule enclosing the carcinoma;...
Keratin, type I cytoskeletal 10 also known as cytokeratin-10 (CK-10) or keratin-10 (K10) is a protein that in humans is encoded by the KRT10 gene. Keratin...
and binds to Keratin 10, a Type I keratin, to form a coiled coil heterotypic keratin chain. Keratin 1 and Keratin 10 are specifically expressed in the...
Keratin 5, also known as KRT5, K5, or CK5, is a protein that is encoded in humans by the KRT5 gene. It dimerizes with keratin 14 and forms the intermediate...
8 introns and is located in the type II keratin gene cluster on human chromosome 12q. Keratin6A and keratin 6B are encoded by the neighbouring genes...
Keratin 3 also known as cytokeratin 3 is a protein that in humans is encoded by the KRT3 gene. Keratin 3 is a type II cytokeratin. It is specifically found...
Type II keratins (or Type II cytokeratins) constitutes the Type II intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present...
Keratin 16 is a protein that in humans is encoded by the KRT16 gene. Keratin 16 is a type I cytokeratin. It is paired with keratin 6 in a number of epithelial...
Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene....
Keratin 12 is a protein that in humans is encoded by the KRT12 gene. Keratin 12 is keratin found expressed in corneal epithelia. Mutations in the gene...
Keratin 13 (or cytokeratin 13) is a protein that in humans is encoded by the KRT13 gene. Keratin 13 is a type I cytokeratin, it is paired with keratin...
a human epidermal keratin derived from cloned cDNAs. Analysis of a second keratin sequence revealed that the two types of keratins share only about 30%...
Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene. Keratin 4...
Keratin 21 is a type I cytokeratin which expresses immunologically specific fusion protein. It is not found in humans, but only in Rattus norvegicus....
Keratin 15 is a protein that in humans is encoded by the KRT15 gene. It has also been referred to as cytokeratin 15, K1CO and KRTB. Keratin 15 is a type...
Type I keratins (or Type I cytokeratins) are cytokeratins that constitute the Type I intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton...
intermediate filaments are in general present in mesenchymal cells. made of keratin. Keratin is present in general in epithelial cells. neurofilaments of neural...
Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. Keratin 20 is a type I cytokeratin. It is a major cellular...
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