Kanamycin A,[2] often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis.[3] It is not a first line treatment.[3] It is used by mouth, injection into a vein, or injection into a muscle.[3] Kanamycin is recommended for short-term use only, usually from 7 to 10 days.[3] As with most antibiotics, it is ineffective in viral infections.[3]
Common side effects include hearing and balance problems.[3] Kidney problems may also occur.[3] Kanamycin is not recommended during pregnancy as it may harm the baby.[3] It is likely safe during breastfeeding.[4] Kanamycin is in the aminoglycoside family of medications.[3] It works by blocking the production of proteins that are required for bacterial survival.[3]
Kanamycin was first isolated in 1957 by Hamao Umezawa from the bacterium Streptomyces kanamyceticus.[3][5] It was removed from the World Health Organization's List of Essential Medicines in 2019.[6][7] It is no longer marketed in the United States.[3]
^"Antibiotic abbreviations list". Retrieved 22 June 2023.
^Elks J, Ganellin DR (1990). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 717–. doi:10.1007/BF00171763. S2CID 122125855.
^ abcdefghijkl"Kanamycin Sulfate". The American Society of Health-System Pharmacists. Archived from the original on 10 September 2017. Retrieved 6 December 2016.
^"Kanamycin (Kantrex) Use During Pregnancy". www.drugs.com. Archived from the original on 20 December 2016. Retrieved 7 December 2016.
^Sneader W (2005). Drug Discovery: A History. John Wiley & Sons. p. 302. ISBN 9780471899792.
^World Health Organization (2019). Executive summary: the selection and use of essential medicines 2019: report of the 22nd WHO Expert Committee on the selection and use of essential medicines. Geneva: World Health Organization. hdl:10665/325773. WHO/MVP/EMP/IAU/2019.05. License: CC BY-NC-SA 3.0 IGO.
^World Health Organization (2019). The selection and use of essential medicines: report of the WHO Expert Committee on Selection and Use of Essential Medicines, 2019 (including the 21st WHO Model List of Essential Medicines and the 7th WHO Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl:10665/330668. ISBN 9789241210300. ISSN 0512-3054. WHO technical report series;1021.
KanamycinA, often referred to simply as kanamycin, is an antibiotic used to treat severe bacterial infections and tuberculosis. It is not a first line...
phosphate from ATP to the 3'-hydroxyl group of a 4,6-disubstituted aminoglycoside, such as kanamycin. However, APH(3') has also been found to phosphorylate...
Health Organization's List of Essential Medicines. It is derived from kanamycin. Amikacin is most often used for treating severe infections with multidrug-resistant...
which confers resistance to certain aminoglycoside antibiotics including kanamycin and neomycin. On May 18, 1994, the FDA completed its evaluation of the...
In molecular biology, kanamycin nucleotidyltransferase EC 2.7.7.- (KNTase) is an enzyme which is involved in conferring resistance to aminoglycoside antibiotics...
genetically modified organism in 1973, a bacterium resistant to the antibiotic kanamycin. The first genetically modified animal, a mouse, was created in 1974 by...
Bekanamycin (INN; kanamycin B) is an aminoglycoside antibiotic. Morales MA, Castrillon JL, Hernandez DA (1993). "Effects of bekanamycin and dibekacin...
transplantation of human cord blood CD133+ cells to nod-scid mice made deaf with kanamycin and noise". Cell Transplant. 17 (6): 665–678. doi:10.3727/096368908786092685...
with various industry-grade antimicrobial chemicals, like ceftriaxone, kanamycin, and gentamicin, at several levels of magnitude greater than the planktonic...
such as Kanamycin, Erythromycin, or Oxytetracycline, and in extreme cases, antibiotic injections. Velvet, also known as gold dust disease, is a prevalent...
examples of aminoglycosides include the deoxystreptamine-containing agents kanamycin, tobramycin, gentamicin, and neomycin (see below). Aminoglycosides that...
cell membranes. Neomycin resistance is conferred by either one of two kanamycin kinase genes. Genes conferring neomycin-resistance are commonly included...
resistance to antibiotics such as ampicillin, chloramphenicol, tetracycline, kanamycin, etc., are considered useful selectable markers for E. coli. The non-recombinants...
The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly...
anti-addictive drug, as well as its occasional recreational use as a dissociative.[citation needed] Kanamycin is an aminoglycoside antibiotic which induces deafness...
4'-dideoxykanamycin B) is an aminoglycoside antibiotic. It is a semisynthetic derivative of kanamycin developed by Hamao Umezawa and collaborators for Meiji...
ethambutol, and pyrazinamide. For drug-resistant TB, a combination of antibiotics such as amikacin, kanamycin, or capreomycin should be used. The most common...
infections due to Chlamydia trachomatis or Neisseria gonorrhoeae. Amikacin, kanamycin, netilmicin, and tobramycin are alternatives Alternatives are 4th level...
subspecies are resistant to nalidixic acid, penicillin G, oxacillin, kanamycin, and streptomycin. They were also somewhat resistant to methicillin and...
selectable markers, for example the plasmid pACYC177 has both ampicillin and kanamycin resistance gene. Shuttle vector which is designed to be maintained in...
O'Rourke kan, PDP ligand, kanamycinA Iwasawa decomposition of a Lie group in mathematics A Japanese unit of mass (貫) Kan, a Korean unit of length Dated...
pyrosequencing of the 16S rRNA gene, and no negative relationship when kanamycin was added. Polystyrene foam decreases T. molitor fecundity, but the beetle...
but it will typically be a gene granting cells a detoxification capacity for certain herbicides or antibiotics such as kanamycin, hygromycin B, or glyphosate[page needed]...
displayed at least some resistance include chloramphenicol, streptomycin, kanamycin, gentamicin, tetracycline, spectinomycin and neomycin. However, other...
susceptibility to several antibiotics, such as colistin sulphate, clindamycin and kanamycinA or penicillin has been reported. Page Species: Anaerococcus murdochii...
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