Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Isothiazole, or 1,2-thiazole, is an organic compound consisting with the formula (CH)3S(N). The ring is unsaturated and features an S-N bond.[4] The isomeric thiazole, where the S and N are not directly bonded are far more common.
Isothiazones are produced by oxidation of enamine-thiones.[5]
The ring structure of isothiazole is incorporated into larger compounds with biological activity such as the pharmaceutical drugs ziprasidone and perospirone.
^International Union of Pure and Applied Chemistry (2014). Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013. The Royal Society of Chemistry. p. 140. doi:10.1039/9781849733069. ISBN 978-0-85404-182-4.
^Zoltewicz, J. A. & Deady, L. W. Quaternization of heteroaromatic compounds. Quantitative aspects. Adv. Heterocycl. Chem. 22, 71-121 (1978)
^Isothiazoles, D. W. Brown and M. Sainsbury, page 513
^Heterocyclic Chemistry, 3rd Edition, J.A. Joule, K. Mills, and G.F. Smith, page 394
^Kaur, Navjeet (2023). "Five-membered S,N-heterocycles". 5-Membered Heterocycle Synthesis Using Iodine. pp. 435–472. doi:10.1016/B978-0-443-18941-8.00007-9. ISBN 9780443189418.
Isothiazole, or 1,2-thiazole, is an organic compound consisting with the formula (CH)3S(N). The ring is unsaturated and features an S-N bond. The isomeric...
the formula (CH)2SN(H)CO. A white solid, it is structurally related to isothiazole. Isothiazolone itself is of limited interest, but several of its derivatives...
the formula C6H4SN(H)CO. A white solid, it is structurally related to isothiazole, and is part of a class of molecules called isothiazolinones. BIT is...
which is nitrogen, are collectively called the azoles. Thiazoles and isothiazoles contain a sulfur and a nitrogen atom in the ring. Dithiolanes have two...
generated salt giving the impression of a H–X insertion. The reported stable isothiazole carbene (2b) derived from an isothiazolium perchlorate (1) was questioned...
hydroxylation of the cyclohexane ring and reductive cleavage of the isothiazole ring followed by S-methylation. The two relevant active metabolites are...
C3H3NS (molar mass: 85.13 g/mol, exact mass: 84.9986 u) may refer to: Isothiazole, or 1,2-thiazole Thiazole, or 1,3-thiazole This set index page lists...
electron deficient dipolariphile to give stable heterocycles such as isothiazole (seen below). The intermediate has been successfully trapped using other...
involving benzalkonium chloride, miristalkonium chloride, and 2-octyl-2H-isothiazole-3-one, which resulted in a net decrease of fifty percent of the fungus...
dithietanes, thiolanes, thianes, dithianes, thiepanes, thiepines, thiazoles, isothiazoles, and thiophenes, among others. The latter three compounds represent a...
However, the specialized reagent 2-fluoro-3,3-dimethyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide consistently affords better yields of monofluorinated carbonyl...
Thiomuscimol is a GABAA receptor agonist which is structurally related to muscimol. Lykkeberg, Jytte; Krogsgaard-Larsen, Povl; Garegg, Per J.; Norberg...
Amflutizole is a xanthine oxidase inhibitor used for the treatment of gout. O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994)....
name 2-(3-(4-(p-Fluorophenyl)-1-piperazinyl)propyl)-2H-naphth(1,8-cd)isothiazole 1,1-dioxide CAS Number 127625-29-0 Y PubChem CID 60785 IUPHAR/BPS 5434...
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