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Isothiazolinone information


Isothiazolinone
Skeletal formula of isothiazolinone
Space-filling model of the isothiazolinone molecule
Names
Preferred IUPAC name
1,2-Thiazol-3(2H)-one
Other names
Isothiazolin-3-one; 3(2H)-Isothiazolone, isothiazolin
Identifiers
CAS Number
  • 1003-07-2 checkY
3D model (JSmol)
  • Interactive image
  • Interactive image
ChemSpider
  • 87509 ☒N
ECHA InfoCard 100.225.492 Edit this at Wikidata
EC Number
  • 696-206-9
MeSH C001490
PubChem CID
  • 96917
UNII
  • E57JT172V7 ☒N
CompTox Dashboard (EPA)
  • DTXSID9074935 Edit this at Wikidata
InChI
  • InChI=1S/C3H3NOS/c5-3-1-2-6-4-3/h1-2H,(H,4,5) ☒N
    Key: MGIYRDNGCNKGJU-UHFFFAOYSA-N ☒N
  • InChI=1/C3H3NOS/c5-3-1-2-6-4-3/h1-2H,(H,4,5)
    Key: MGIYRDNGCNKGJU-UHFFFAOYAO
SMILES
  • O=C1NSC=C1
  • c1csnc1O
Properties
Chemical formula
C3H3NOS
Molar mass 101.127
Appearance white solid
Melting point 74–75 °C (165–167 °F; 347–348 K)
Hazards
GHS labelling:
Pictograms
GHS07: Exclamation mark
Signal word
Warning
Hazard statements
H302, H312, H315, H319, H332, H335
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO. A white solid, it is structurally related to isothiazole. Isothiazolone itself is of limited interest, but several of its derivatives are widely used preservatives and antimicrobials.[1]

  1. ^ Silva, Vânia; Silva, Cátia; Soares, Pedro; Garrido, E. Manuela; Borges, Fernanda; Garrido, Jorge (2020). "Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles". Molecules. 25 (4): 991. doi:10.3390/molecules25040991. PMC 7070760. PMID 32102175.

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Isothiazolinone

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Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO. A white solid, it is structurally related to isothiazole...

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Methylisothiazolinone

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organic compound with the formula S(CH)2C(O)NCH3. It is a white solid. Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal...

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Dichlorooctylisothiazolinone

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It is a white solid that melts near room temperature. It is an isothiazolinone, a class of heterocyclic compounds used as biocides. DCOIT has attracted...

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Methylchloroisothiazolinone

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a white solid that melts near room temperature. The compound is an isothiazolinone, a class of heterocycles used as biocides. These compounds have an...

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Benzisothiazolinone

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related to isothiazole, and is part of a class of molecules called isothiazolinones. BIT is widely used as a preservative and antimicrobial. Benzisothiazolinone...

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Isothiazole

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activity such as the pharmaceutical drugs ziprasidone and perospirone. Isothiazolinone International Union of Pure and Applied Chemistry (2014). Nomenclature...

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Organotin chemistry

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Pedro; Garrido, E. Manuela; Borges, Fernanda; Garrido, Jorge (2020). "Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles". Molecules...

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Preservative

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and personal care products use broad-spectrum preservatives, such as isothiazolinones and formaldehyde releasers, which may cause sensitization, leading...

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Fouling

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important unoxidizable biocides is a mixture of chloromethyl-isothiazolinone and methyl-isothiazolinone. Also applied are dibrom nitrilopropionamide and quaternary...

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Allergic contact dermatitis

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precious metal and compound often found in jewelry and dental materials Isothiazolinones – preservatives used in many personal care, household, and commercial...

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Toxicant

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to drinking water to disinfect it. Non-oxidizing toxicants include isothiazolinones and quaternary ammonium compounds. An intoxicant is a substance that...

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Air freshener

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These can include: parabens such as methylparaben and propylparaben isothiazolinones such as methylisothiazoline and benzisothiazolinone formaldehyde releasers...

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Polymer stabilizer

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involves its own class of special bio-stabilizers and biocides (e.g. isothiazolinones). Oil additives and fuel additives often include antioxidant stabilizers...

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MELISA

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Forsbeck M, Nilsson R. Lymphocyte transformation test for diagnosis of isothiazolinone allergy in man. J Invest Dermatol 1990; 94: 798–802. Stejskal V, Cederbrant...

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