Medical condition when the fetus is deprived of sufficient oxygen
Medical condition
Intrauterine hypoxia
Micrograph of a placental infarct (left of image), a cause of intrauterine hypoxia. H&E stain.
Specialty
Pediatrics
Intrauterine hypoxia (also known as fetal hypoxia) occurs when the fetus is deprived of an adequate supply of oxygen. It may be due to a variety of reasons such as prolapse or occlusion of the umbilical cord, placental infarction, maternal diabetes (prepregnancy or gestational diabetes)[1] and maternal smoking. Intrauterine growth restriction may cause or be the result of hypoxia. Intrauterine hypoxia can cause cellular damage that occurs within the central nervous system (the brain and spinal cord). This results in an increased mortality rate, including an increased risk of sudden infant death syndrome (SIDS). Oxygen deprivation in the fetus and neonate have been implicated as either a primary or as a contributing risk factor in numerous neurological and neuropsychiatric disorders such as epilepsy, attention deficit hyperactivity disorder, eating disorders and cerebral palsy.[2][3][4][5][6][7]
^Tarvonen M, Hovi P, Sainio S, Vuorela P, Andersson S, Teramo K (2021). "Intrapartal cardiotocographic patterns and hypoxia-related perinatal outcomes in pregnancies complicated by gestational diabetes mellitus". Acta Diabetologica. 58 (11): 1563–1573. doi:10.1007/s00592-021-01756-0. PMC 8505288. PMID 34151398.{{cite journal}}: CS1 maint: multiple names: authors list (link)
^Maslova MV, Maklakova AS, Sokolova NA, Ashmarin IP, Goncharenko EN, Krushinskaya YV (July 2003). "The effects of ante- and postnatal hypoxia on the central nervous system and their correction with peptide hormones". Neuroscience and Behavioral Physiology. 33 (6): 607–11. doi:10.1023/A:1023938905744. PMID 14552554. S2CID 1170955.
^Habek D, Habek JC, Jugović D, Salihagić A (2002). "[Intrauterine hypoxia and sudden infant death syndrome]". Acta Medica Croatica. 56 (3): 109–18. PMID 12630342.
^Bulterys MG, Greenland S, Kraus JF (October 1990). "Chronic fetal hypoxia and sudden infant death syndrome: interaction between maternal smoking and low hematocrit during pregnancy". Pediatrics. 86 (4): 535–40. doi:10.1542/peds.86.4.535. PMID 2216618. S2CID 245156371.
^Peleg D, Kennedy CM, Hunter SK (August 1998). "Intrauterine growth restriction: identification and management". American Family Physician. 58 (2): 453–60, 466–7. PMID 9713399.
^Rosenberg A (June 2008). "The IUGR newborn". Seminars in Perinatology. 32 (3): 219–24. doi:10.1053/j.semperi.2007.11.003. PMID 18482625.
^Gonzalez FF, Miller SP (November 2006). "Does perinatal asphyxia impair cognitive function without cerebral palsy?". Archives of Disease in Childhood. Fetal and Neonatal Edition. 91 (6): F454-9. doi:10.1136/adc.2005.092445. PMC 2672766. PMID 17056843.
and 27 Related for: Intrauterine hypoxia information
Intrauterinehypoxia (also known as fetal hypoxia) occurs when the fetus is deprived of an adequate supply of oxygen. It may be due to a variety of reasons...
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development can be impaired by a number of maternal implications. Rubella, intrauterinehypoxia and hypothyroidism are some of the more researched examples. Alcohol...
neurodevelopmental disorders, including schizophrenia, in the child. Intrauterinehypoxia, or oxygen deprivation in the womb, can cause serious brain damage...
Intrauterine growth restriction (IUGR), or fetal growth restriction, is the poor growth of a fetus while in the womb during pregnancy. IUGR is defined...
it a leading cause of death for newborns. In the United States, intrauterinehypoxia and birth asphyxia was listed as the tenth leading cause of neonatal...
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fall and carbon dioxide rises, resulting in rising blood acid levels and hypoxia. Structural immaturity, as manifested by a decreased number of gas exchange...
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placental infarction, maternal anemia and cardiac problems may cause intrauterinehypoxia, umbilical cord occlusion or cord prolapse may cause ischemia, resulting...
Damian; Kingdom, John; Jaeggi, Edgar (2010). "Causes and Mechanisms of IntrauterineHypoxia and Its Impact on the Fetal Cardiovascular System: A Review". International...
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widely used to assess fetal well-being by identifying babies at risk of hypoxia (lack of oxygen). CTG is mainly used during labour. A review found that...
mandated definitions. The basic WHO definition of fetal death is the intrauterine death of any conceptus at any time during pregnancy. However, for practical...
oxidative enzymes. There are a range of responses to hypoxia at the cellular level, shown by discovery of hypoxia-inducible factors (HIFs), which determine the...
sphincter, which results in the passage of meconium. Then, because of intrauterine gasping or from the first few breaths after delivery, MAS may develop...
danger to the fetus and to delivery. Treatment primarily consists of intrauterine resuscitation, the goal of which is to restore oxygenation of the fetus...
support them. Glassman and Lim have trouble finding the source of the intrauterine bleeding and prepare to perform a hysterectomy, but are able to save...
some of these data while trying to focus on the immature brain. Cerebral hypoxia-ischaemia results in reduced cerebral oxidative metabolism, cerebral lactic...
complications that compound hypoxia or acidosis in the fetus, a fetus with a already compromised baseline oxygenation due to intrauterine growth restriction,...
result of neuronal migration disorders during early brain development, intrauterine disturbances, perinatal injuries, and other central nervous system disorders...
susceptibility of the fetus to intrapartum hypoxia, regardless of the size of the fetus. The risk of hypoxia and the resulting risk of poor condition in...
reserves. This can result in increased risk of caesarean delivery, fetal hypoxia, and perinatal death in pregnancies with velamentous cord insertion. Damage...
literature on a wide range of prenatal risk factors, such as prenatal stress, intrauterine (in the womb) malnutrition, and prenatal infection. Increased paternal...
4th to the 12th week of intrauterine life. Clefts of the primary palate develop between the 4th and 7th weeks of intrauterine life, while clefts of the...
contraction squeezes the blood vessels, reducing blood flow and causing some hypoxia. During the later stages of gestation, there is an increase in abundance...