Internexin neuronal intermediate filament protein, alpha Symbol INA Alt. symbols NEF5 NCBI gene 9118 HGNC 6057 OMIM 605338 RefSeq NM_032727 UniProt Q16352 Locus Chr. 10 q24 Structures Swiss-model Domains InterPro
Internexin , alpha-internexin , is a Class IV intermediate filament approximately 66 KDa. The protein was originally purified from rat optic nerve and spinal cord.[1] The protein copurifies with other neurofilament subunits, as it was originally discovered, however in some mature neurons it can be the only neurofilament expressed. The protein is present in developing neuroblasts and in the central nervous system of adults. The protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers.
^ Levavasseur F, Zhu Q, and JP Julien. No requirement of alpha-internexin for nervous system development and for radial growth of axons. Molecular Brain Research. 69:104-112. (1999).
Last Update: 2022-07-26T19:59:42Z
Internexin , alpha-internexin , is a Class IV intermediate filament approximately 66 KDa. The protein was originally purified from rat optic nerve and spinal...
Word Count : 974
Last Update: 2023-08-31T11:02:28Z
Type IV consists of the neurofilament proteins NF-L, NF-M, NF-H and α-internexin . Type V consists of the nuclear lamins, and type VI consists of the protein...
Word Count : 2579
Last Update: 2024-05-21T07:41:08Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 3016
Last Update: 2024-01-27T10:03:39Z
There are four major neurofilament subunits, NF-L, NF-M, NF-H and α-internexin . These form heteropolymers which assemble to produce 10nm neurofilaments...
Word Count : 2153
Last Update: 2024-05-06T05:02:12Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 4894
Last Update: 2024-04-19T19:25:25Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 3649
Last Update: 2024-05-23T16:24:37Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 2777
Last Update: 2024-04-20T07:37:29Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 2154
Last Update: 2024-02-22T06:58:08Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 7838
Last Update: 2024-05-27T06:34:30Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 5121
Last Update: 2024-04-26T06:22:51Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 6277
Last Update: 2024-02-12T12:44:15Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 17979
Last Update: 2023-10-15T18:04:10Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 1711
Last Update: 2024-04-25T00:04:14Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 4235
Last Update: 2023-11-28T02:55:01Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 3354
Last Update: 2024-05-06T01:48:50Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 3225
Last Update: 2023-12-31T16:37:07Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 974
Last Update: 2024-04-19T20:38:51Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 631
Last Update: 2024-04-25T14:29:26Z
signals to the nucleus. Syncoilin is an atypical type III IF protein. Alpha-internexin Neurofilaments – the type IV family of intermediate filaments that is...
Word Count : 3168
Last Update: 2023-09-10T18:54:03Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 73
Last Update: 2023-08-31T18:37:41Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 346
Last Update: 2023-10-04T03:48:48Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 73
Last Update: 2024-04-03T19:42:49Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 2529
Last Update: 2023-12-02T21:30:25Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 3239
Last Update: 2024-04-01T06:52:41Z
(Keratin, Cytokeratin) Type 3 Desmin GFAP Peripherin Vimentin Type 4 Internexin Nestin Neurofilament NEFL NEFM NEFH Synemin Syncoilin Type 5 Nuclear lamins:...
Word Count : 2655
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