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Kinesin information


The kinesin dimer (red) attaches to, and moves along, microtubules (blue and green).
Animation of kinesin "walking" on a microtubule

A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme). The active movement of kinesins supports several cellular functions including mitosis, meiosis and transport of cellular cargo, such as in axonal transport, and intraflagellar transport. Most kinesins walk towards the plus end of a microtubule, which, in most cells, entails transporting cargo such as protein and membrane components from the center of the cell towards the periphery.[1] This form of transport is known as anterograde transport. In contrast, dyneins are motor proteins that move toward the minus end of a microtubule in retrograde transport.

  1. ^ Berg J, Tymoczko JL, Stryer L (2002). "Kinesin and Dynein Move Along Microtubules". Biochemistry. 5th Edition.

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Kinesin

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A kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells. Kinesins move along microtubule (MT) filaments and are powered...

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Kinesin 13

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The Kinesin-13 Family are a subfamily of motor proteins known as kinesins. Most kinesins transport materials or cargo around the cell while traversing...

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Motor protein

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behind most active transport of proteins and vesicles in the cytoplasm. Kinesins and cytoplasmic dyneins play essential roles in intracellular transport...

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Kinesin 8

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The Kinesin 8 Family are a subfamily of the molecular motor proteins known as kinesins. Most kinesins transport materials or cargo around the cell while...

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KIF13B

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Kinesin family member 13B is a protein that in humans is encoded by the KIF13B gene. GRCh38: Ensembl release 89: ENSG00000197892 – Ensembl, May 2017 GRCm38:...

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Kinesin ATP phosphohydrolase

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Kinesin ATP phosphohydrolase may refer to: Plus-end-directed kinesin ATPase, an enzyme Minus-end-directed kinesin ATPase, an enzyme This set index page...

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Monastrol

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lab of Tim Mitchison. Monastrol was shown to inhibit the kinesin-5 (also known as KIF11, Kinesin Eg5), a motor protein important for spindle bipolarity...

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KIF18B

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Kinesin family member 18B (KIF18B), also known as kinesin-8, is a human protein encoded by the KIF18B gene. It is part of the kinesin family of motor...

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Axonal transport

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the axon and provide the main cytoskeletal "tracks" for transportation. Kinesin and dynein are motor proteins that move cargoes in the anterograde (forwards...

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KIF26A

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Kinesin family member 26A (KIF26A), also known as kinesin-11, is a human protein encoded by the KIF26A gene. It is part of the kinesin family of motor...

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KIF20A

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Kinesin-like protein KIF20A is a protein that in humans is encoded by the KIF20A gene. KIF20A has been shown to interact with RAB6A. GRCh38: Ensembl release...

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Phragmoplast

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antiparallel MT bundling at the phragmoplast midline are MAP65-3 and kinesin-5. The kinesin-7 family proteins, HINKEL/AtNACK1 and AtNACK2/TES, recruit a mitogen-activated...

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KIF21B

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Kinesin family member 21B (KIF21B), also known as kinesin-4, is a human protein encoded by the KIF21B gene. It is part of the kinesin family of motor...

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KIF5B

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Kinesin family member 5B (KIF5B) is a protein that in humans is encoded by the KIF5B gene. It is part of the kinesin family of motor proteins. KIF5B has...

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KIF3C

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Kinesin-like protein KIF3C is a protein that in humans is encoded by the KIF3C gene. It is part of the kinesin family of motor proteins. GRCh38: Ensembl...

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KIF3B

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Kinesin-like protein KIF3B is a protein that in humans is encoded by the KIF3B gene. KIF3B is an N-type protein that complexes with two other kinesin...

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KIF5A

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Kinesin family member 5A is a protein that in humans is encoded by the KIF5A gene. It is part of the kinesin family of motor proteins. This gene encodes...

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Eukaryote

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cortical layers and bundles. Motor proteins of microtubules, dynein and kinesin, and myosin of actin filaments, provide dynamic character of the network...

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KIF1A

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Kinesin-like protein KIF1A, also known as axonal transporter of synaptic vesicles or microtubule-based motor KIF1A, is a protein that in humans is encoded...

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KIFC1

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Kinesin-like protein KIFC1 is a protein that in humans is encoded by the KIFC1 gene. The protein KifC1 is a member of kinesin-14 family. KifC1 consists...

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KIF3A

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Kinesin-like protein KIF3A is a protein that in humans is encoded by the KIF3A gene. KIF3A is one subunit of the heterotrimeric motor protein, kinesin-2...

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KIF2C

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Kinesin-like protein KIF2C is a protein that in humans is encoded by the KIF2C gene. The protein encoded by this gene is a member of kinesin-like protein...

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Jonathon Howard

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showed that kinesin moves processively, taking several hundred steps along a microtubule before dissociating. This finding explained how kinesin could carry...

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Spindle apparatus

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includes the spindle microtubules, associated proteins, which include kinesin and dynein molecular motors, condensed chromosomes, and any centrosomes...

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Microtubule

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proteins that bind to microtubules, including the motor proteins dynein and kinesin, microtubule-severing proteins like katanin, and other proteins important...

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GTPase

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additional N-terminal strands. Both namesakes of this superfamily, myosin and kinesin, have shifted to use ATP. See dynamin as a prototype for large monomeric...

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