The two protein filaments of myofibrils in muscle cells
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Myofilament
Myofilament
Details
Part of
Myofibril
Identifiers
Latin
myofilamentum
TH
H2.00.05.0.00006
FMA
67897
Anatomical terms of microanatomy
[edit on Wikidata]
Myofilaments are the three protein filaments of myofibrils in muscle cells. The main proteins involved are myosin, actin, and titin. Myosin and actin are the contractile proteins and titin is an elastic protein. The myofilaments act together in muscle contraction, and in order of size are a thick one of mostly myosin, a thin one of mostly actin, and a very thin one of mostly titin.[1][2]
Types of muscle tissue are striated skeletal muscle and cardiac muscle, obliquely striated muscle (found in some invertebrates), and non-striated smooth muscle.[3] Various arrangements of myofilaments create different muscles. Striated muscle has transverse bands of filaments. In obliquely striated muscle, the filaments are staggered. Smooth muscle has irregular arrangements of filaments.
^Cite error: The named reference Saladin was invoked but never defined (see the help page).
^Kellermayer, D; Smith JE, 3rd; Granzier, H (May 2019). "Titin mutations and muscle disease". Pflügers Archiv: European Journal of Physiology. 471 (5): 673–682. doi:10.1007/s00424-019-02272-5. PMC 6481931. PMID 30919088.{{cite journal}}: CS1 maint: numeric names: authors list (link)
^Cao, T; Thongam, U; Jin, JP (15 May 2019). "Invertebrate troponin: Insights into the evolution and regulation of striated muscle contraction". Archives of Biochemistry and Biophysics. 666: 40–45. doi:10.1016/j.abb.2019.03.013. PMC 6529277. PMID 30928296.
Myofilaments are the three protein filaments of myofibrils in muscle cells. The main proteins involved are myosin, actin, and titin. Myosin and actin are...
actin myofilaments along each other. Each myofibril has a diameter of between 1 and 2 micrometres (μm). The filaments of myofibrils, myofilaments, consist...
Solar filament, a solar prominence seen against the disc of the sun Myofilament, filaments of myofibrils constructed from proteins Protein filament,...
part of the troponin protein complex, where it binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Troponin I prevents myosin...
muscle myofilaments of myosin and actin slide past each other, pulling the Z-lines together. During an eccentric contraction, the myofilaments slide past...
efficient. This is due to reduced ability to cross-link actin and myosin myofilaments in over-stretched heart muscle. No diagnostic criteria have been agreed...
myofibrils consisting of long protein chains of myofilaments. There are three types of myofilaments: thin, thick, and elastic that work together to produce...
exerts higher calcium sensitivity of actomyosin ATPase activity and myofilament force production, compared with the adult cardiac TnT, as well as a higher...
head is the part of the thick myofilament made up of myosin that acts in muscle contraction, by sliding over thin myofilaments of actin. Myosin is the major...
store, the sarcoplasmic reticulum. The rise in calcium causes the cell's myofilaments to slide past each other in a process called excitation-contraction coupling...
muscle contraction to release and the body to relax. Decomposition of the myofilaments occurs between 48 and 60 hours after the peak of rigor mortis, which...
contractility". Archives of Biochemistry and Biophysics. Special Issue: Myofilament Modulation of Contraction. 601: 11–21. doi:10.1016/j.abb.2016.02.004...
myofibrils. The myofibrils are composed of actin and myosin filaments called myofilaments, repeated in units called sarcomeres, which are the basic functional...
sarcoplasmic reticulum as well as increasing the sensitivity of cardiac myofilaments to Ca2+. Patients with acute decompensated heart failure have diminished...
type 3 nemaline myopathy, congenital myopathy with an excess of thin myofilaments (CM) and congenital myopathy with fibre type disproportion (CMFTD). Mutations...
mutations occurring in the genes encoding for the sarcomere. In the thick myofilaments of the heart tissue, the predominant gene mutations occur in “myosin-binding...
of the cardiomyocyte such as calcium channels and components of the myofilaments. Phosphorylation of calcium channels permits an increase in calcium influx...
form a troponin-tropomyosin complex Troponin I binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place Smooth muscle does not...
sarcomere. Each muscle cell contains myofibrils composed of actin and myosin myofilaments repeated as a sarcomere. Many nuclei are present in each muscle cell...
the layer are rather poorly differentiated, contain only a few tiny myofilaments and are thereby unlikely to contribute actively to the process of post-natal...
appears in between the I-bands as a dark line that anchors the actin myofilaments. Surrounding the Z-line is the region of the I-band (for isotropic)....
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