An intercellular cleft is a channel between two cells through which molecules may travel and gap junctions and tight junctions may be present. Most notably, intercellular clefts are often found between epithelial cells and the endothelium of blood vessels and lymphatic vessels, also helping to form the blood-nerve barrier surrounding nerves. Intercellular clefts are important for allowing the transportation of fluids and small solute matter through the endothelium.
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An intercellularcleft is a channel between two cells through which molecules may travel and gap junctions and tight junctions may be present. Most notably...
fluid and blood via diffusion across gaps in capillary walls called intercellularclefts; thus, the blood and interstitial fluid are in dynamic equilibrium...
smaller molecules, such as water and ions, to pass through their intercellularclefts. Lipid-soluble molecules can passively diffuse through the endothelial...
directly beneath the dermal-epidermal junction. Achantholytic: Intercellularclefts or lacunae in the lowermost epidermal layer that result from anaplastic...
authoritative information about signaling pathways in human cells. Intercellular+Signaling+Peptides+and+Proteins at the U.S. National Library of Medicine...
granulosum that facilitates intercellular adhesion between keratinocytes. The resulting vesicle is an intraepidermal cleft located above the basal cells...
allowing only small molecules like ions or water to diffuse through the intercellularclefts (the gaps between the endothelial cells). In fenestrated and sinusoidal...
Within the blood islands, lumens begin to appear by the growth of intercellularclefts. The flattened cells at the periphery form the endothelium. Mesenchymal...
synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and...
between them across the walls of capillaries, through pores and capillary clefts. Interstitial fluid consists of a water solvent containing sugars, salts...
neurotransmitters from the presynaptic axon terminal into the synaptic cleft, as in a chemical synapse. The excitatory neurotransmitters, the most common...
initially entirely of SNARE proteins, the pore is easily able to undergo intercellular regulation, making fluctuation and "kiss-and-run" mechanisms easily...
neurotransmitters are typically released from synaptic vesicles into the synaptic cleft via exocytosis; however, neurotransmitters can also be released via reverse...
and targets other pancreatic cells. Juxtacrine signaling is a type of intercellular communication that is transmitted via oligosaccharide, lipid, or protein...
non-homologous end joining used mainly at later developmental stages Intercellular communication between developing neurons and microglia is also indispensable...
synaptic cleft and binds to ACh receptors on the post-synaptic membrane, relaying the signal from the nerve. AChE is concentrated in the synaptic cleft, where...
Continue in corresponding section: It is characterized by epithelial intercellular edema. In addition to above, an unspecific spongiotic dermatitis can...
binds halfway between the nucleotide binding pocket and the actin binding cleft of myosin, predominantly in an actin detached conformation. This type of...
to form a fibronectin receptor. CD49f Integrin alpha 6 subunit. CD50 Intercellular adhesion molecule 3 encoded by the ICAM3 gene. CD51 CD51 is a type I...
H+-atpase (ductin) is accompanied by down-regulation of gap junctional intercellular communication and translocation of connexin 43 in NIH3T3 cells". Oncogene...
The tissue is skin from a patient with Pemphigus vulgaris. Note the intercellular IgG deposits in the epidermis and the early intraepidermal vesicle caused...
ISBN 978-0-521-62634-7. Levitan, Irwin; Kaczmarek, Leonard (19 August 2015). "Intercellular communication". The Neuron: Cell and Molecular Biology (4th ed.). New...
with multiple components of T-cell receptor (TCR) complex, mediates intercellular signaling pathways and negatively regulates its function. HAVCR2/TIM-3...
includes degeneration of stratified squamous epithelial cells, the loss of intercellular connections and inflammatory infiltrate around the capillaries of the...
pp. 171–194. MacDonald PE, Rorsman P (February 2006). "Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells". PLOS Biology...
ATP-binding protein (ATP)- and the substrate-binding sites are located in the cleft formed by these two terminal lobes. This is also where the pseudosubstrate...
transported throughout the neuron and can release peptides at the synaptic cleft, cell body, and along the axon. Neuropeptides are released by dense core...
nerve tissue. The tissue has an equal amount of fibers, cells, and intercellular substance. The dense layer is the deeper layer of the lamina propria...
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