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Kappadione information


Kappadione
Clinical data
Routes of
administration
Injection
ATC code
  • none
Legal status
Legal status
  • US: Rx only, discontinued (was FDA approved)
  • In general: ℞ (Prescription only)
Identifiers
IUPAC name
  • Tetrasodium (2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate
CAS Number
  • 6700-42-1 checkY
PubChem CID
  • 8555
DrugBank
  • DB09332 checkY
ChemSpider
  • 8237 ☒N
UNII
  • 2OVL75B30W
KEGG
  • D04908
CompTox Dashboard (EPA)
  • DTXSID80156832 Edit this at Wikidata
ECHA InfoCard100.004.558 Edit this at Wikidata
Chemical and physical data
FormulaC11H8Na4O8P2
Molar mass422.084 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • CC1=C(C2=CC=CC=C2C(=C1)OP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]
InChI
  • InChI=1S/C11H12O8P2.4Na/c1-7-6-10(18-20(12,13)14)8-4-2-3-5-9(8)11(7)19-21(15,16)17;;;;/h2-6H,1H3,(H2,12,13,14)(H2,15,16,17);;;;/q;4*+1/p-4 ☒N
  • Key:GZBACHSOZNEZOG-UHFFFAOYSA-J ☒N
 ☒NcheckY (what is this?)  (verify)

Kappadione is a vitamin K derivative used for the treatment of side effects of vitamin K antagonists such as warfarin, prophylaxis and treatment of vitamin K deficiency bleeding, and hypoprothrombinemia due to various causes.[1] It was manufactured by Eli Lilly and Company.[2] Chemically, it is menadiol sodium diphosphate. It was approved by the US Food and Drug Administration prior to 1982 and marketed by Lilly. It has since been discontinued and is not available in North America.[1]

  1. ^ a b DrugBank DB09332 . Accessed 21 April 2021.
  2. ^ "Kappadione overview, medicine.org". Archived from the original on 2016-03-03. Retrieved 2008-04-14.

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Kappadione

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Kappadione is a vitamin K derivative used for the treatment of side effects of vitamin K antagonists such as warfarin, prophylaxis and treatment of vitamin...

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Menadiol

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menadiol dimalonate, or its various salts, like menadiol sodium diphosphate (Kappadione) menadiol sodium disulfate. Menadiol sodium diphosphate is approved in...

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