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Hypervariable region information


A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case of nuclear DNA) or have substitutions (in the case of mitochondrial DNA). Changes or repeats in the hypervariable region are highly polymorphic.

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Hypervariable region

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A hypervariable region (HVR) is a location within nuclear DNA or the D-loop of mitochondrial DNA in which base pairs of nucleotides repeat (in the case...

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16S ribosomal RNA

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sections of the 16S sequence across different taxa. Although no hypervariable region can accurately classify all bacteria from domain to species, some...

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Framework region

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regions and three of which are hypervariable regions. The framework region makes up about 85% of the variable region. Located on the tips of the Y-shaped...

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Hypervariable

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loci Hypervariable locus, a locus with many alleles; especially those whose variation is due to variable numbers of tandem repeats Hypervariable region (HVR)...

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Hepatitis C virus

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interactions hepatitis C has with the immune system. A hypervariable region, the hypervariable region 1 (HVR1) can be found on the E2 glycoprotein. HVR1 is...

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Mummy Juanita

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TIGR examined two mitochondrial DNA D loop sequences and found that Hypervariable region 1 (HV1) was consistent with mitochondrial haplogroup A2, one of the...

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RHEB

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up the GTPase domain, and the remaining amino acids are part of a hypervariable region ending at the C-terminus in a CAAX motif (C – cysteine, A – aliphatic...

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Infectious bursal disease

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antigenically different IBDVs are clustered in the hypervariable region of VP2. Thus, this hypervariable region of VP2 is the obvious target for the molecular...

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Hypogammaglobulinemia

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(1998). "Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic...

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MtDNA control region

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in hypervariable regions. The average nucleotide diversity in these regions is 1.7%. Despite this variability, an RNA transcript from this region has...

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Hepatitis D

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position : the hypervariable region evolved faster (4.55×10−3 substitutions per site per year) than the hepatitis delta antigen coding region (2.60×10−3 substitutions...

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Mitochondrial Eve

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1999). "Substitution rate variation among sites in mitochondrial hypervariable region I of humans and chimpanzees". Molecular Biology and Evolution. 16...

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Etruscan origins

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Etruscans were a native population. The study extracted and typed the hypervariable region of mitochondrial DNA of 14 individuals buried in two Etruscan necropoleis...

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Family Tree DNA

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[citation needed] FamilyTreeDNA's first mtDNA tests were for HVR1 (hypervariable region 1) of the mtDNA.[citation needed] Eventually, they added a Plus test...

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KRAS

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Hagmann J (September 2000). "Structure and function of the C-terminal hypervariable region of K-Ras4B in plasma membrane targetting and transformation". Oncogene...

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Neanderthal

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Krainitzki, H.; Pääbo, S. (1999). "DNA sequence of the mitochondrial hypervariable region II from the Neandertal type specimen". Proceedings of the National...

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Genetic history of Italy

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Etruscans were a native population. The study extracted and typed the hypervariable region of mitochondrial DNA of 14 individuals buried in two Etruscan necropoleis...

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Molecular mimicry

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example, the QKRAA sequence is an amino acid motif in the third hypervariable region of HLA-DRB1*04:01. This motif is also expressed on numerous proteins...

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Genealogical DNA test

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mitochondrial Haplogroup determination test based on mutations in Hypervariable Region 1 and 2 may establish whether a person's direct female line belongs...

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Index of genetics articles

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Hybridoma Hydrogen bond Hydroxyapatite Hypermorph Hyperploid Hypervariable locus Hypervariable region Hypomorph Hypoploid Hypostatic gene Ichthyosis Identical...

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Genetic saturation

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saturation occurs most rapidly on fast-evolving sequences, such as the hypervariable region of mitochondrial DNA, or in short tandem repeats such as on the Y-chromosome...

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RALA

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100% match in their effector-binding region. The two isoforms mainly differ in the C-terminal hypervariable region, which contains multiple sites for post-translational...

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Algae DNA barcoding

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already been developed, mainly targeting the 18S rRNA. Using the V4 hypervariable region of the ribosomal small subunit DNA (SSU rDNA), DNA-based identification...

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RALB

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100% match in their effector-binding region. The two isoforms mainly differ in the C-terminal hypervariable region, which contains multiple sites for post-translational...

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