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Hepatitis C virus information


Hepacivirus C
Electron micrograph of Hepacivirus C purified from cell culture. Scale bar& = 50 nanometres
Electron micrograph of Hepacivirus C purified from cell culture. Scale bar = 50 nanometres
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Kitrinoviricota
Class: Flasuviricetes
Order: Amarillovirales
Family: Flaviviridae
Genus: Hepacivirus
Species:
Hepacivirus C
Synonyms[1][2]

Hepatitis C virus
HCV
human hepatitis C virus

The hepatitis C virus (HCV)[3] is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans.[4][5]

  1. ^ "Hepacivirus C". National Center for Biotechnology Information (NCBI). Retrieved 3 January 2022.
  2. ^ Smith, Donald B.; et al. (23 June 2016). "Create 13 new species in the genus Hepacivirusand rename 1 species (family Flaviviridae)" (PDF). International Committee on Taxonomy of Viruses (ICTV). Retrieved 13 March 2019.
  3. ^ "Genus: Hepacivirus". International Committee on Taxonomy of Viruses. July 2018. Archived from the original on February 19, 2020.
  4. ^ Ferri, Clodoveo (2015). "HCV syndrome: A constellation of organ- and non-organ specific autoimmune disorders, B-cell non-Hodgkin's lymphoma, and cancer". World Journal of Hepatology. 7 (3): 327–43. doi:10.4254/wjh.v7.i3.327. ISSN 1948-5182. PMC 4381161. PMID 25848462.
  5. ^ Rusyn I, Lemon SM (2014). "Mechanisms of HCV-induced liver cancer: what did we learn from in vitro and animal studies?". Cancer Lett. 345 (2): 210–5. doi:10.1016/j.canlet.2013.06.028. PMC 3844040. PMID 23871966.

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proline-rich hydrophilic phosphoprotein that plays a key role in Hepatitis C virus RNA replication. It appears to be a dimeric form without trans-membrane...

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Nonstructural protein 5B (NS5B) is a viral protein found in the hepatitis C virus (HCV). It is an RNA-dependent RNA polymerase, having the key function...

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protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein. It acts as a serine protease. C-terminal two-thirds of the protein also acts...

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vasculitis. PAN is sometimes associated with infection by the hepatitis B or hepatitis C virus. The condition may be present in infants. PAN is a rare disease...

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E2 is a viral structural protein found in the hepatitis C virus. It is present on the viral envelope and functions as a host receptor binding protein...

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2020 Nobel Prize in Physiology or Medicine

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of Hepatitis C virus." During the award ceremony on December 10, 2020, Prof. Gunilla Karlsson-Hedestam said: "The discovery of the Hepatitis C virus by...

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