Hypogammaglobulinemia is an immune system disorder in which not enough gamma globulins are produced in the blood (thus hypo- + gamma + globulin + -emia). This results in a lower antibody count, which impairs the immune system, increasing risk of infection. Hypogammaglobulinemia may result from a variety of primary genetic immune system defects, such as common variable immunodeficiency,[1] or it may be caused by secondary effects such as medication, blood cancer, or poor nutrition, or loss of gamma globulins in urine, as in nonselective glomerular proteinuria.[medical citation needed] Patients with hypogammaglobulinemia have reduced immune function; important considerations include avoiding use of live vaccines, and take precautionary measures when traveling to regions with endemic disease or poor sanitation such as receiving immunizations, taking antibiotics abroad, drinking only safe or boiled water, arranging appropriate medical cover in advance of travel, and ensuring continuation of any immunoglobulin infusions needed.[2]
^"common variable immunodeficiency" at Dorland's Medical Dictionary
^Barmettler, Sara (14 September 2021). "Hypogammaglobulinemia: Prognosis". Epocrates. Archived from the original on 5 December 2021. Retrieved 31 May 2022.
and 28 Related for: Hypogammaglobulinemia information
Hypogammaglobulinemia is an immune system disorder in which not enough gamma globulins are produced in the blood (thus hypo- + gamma + globulin + -emia)...
between those affected. Its main features are hypogammaglobulinemia and recurrent infections. Hypogammaglobulinemia manifests as a significant decrease in the...
"Good syndrome") is a rare disorder that occurs in adults in whom hypogammaglobulinemia, deficient cell-mediated immunity, and thymoma (usually benign)...
Dwarfism is a condition wherein an organism is exceptionally small, and mostly occurs in the animal kingdom. In humans, it is sometimes defined as an adult...
excess is known as hypergammaglobulinemia. A deficiency is known as hypogammaglobulinemia. A disease of gamma globulins is called a "gammopathy" (for example...
Transient hypogammaglobulinemia of infancy is a form of hypogammaglobulinemia appearing after birth, leading to a reduction in the level of IgG, and also...
Some immune deficiencies, such as X-linked agammaglobulinemia and hypogammaglobulinemia, result in partial or complete lack of antibodies. These diseases...
symptoms depending on the cause, but generally include signs of hypogammaglobulinemia (decrease of one or more types of antibodies) with presentations...
patients may have recurrent respiratory infections associated with hypogammaglobulinemia. Severe thrombotic vascular occlusions may also be found among these...
aplasia and Good syndrome (thymoma with combined immunodeficiency and hypogammaglobulinemia). Other reported disease associations are with acute pericarditis...
people twelve years of age and older with WHIM syndrome (warts, hypogammaglobulinemia, infections and myelokathexis) to increase the number of circulating...
(IgA) deficiency (SIgAD) is a kind of immunodeficiency, a type of hypogammaglobulinemia. People with this deficiency lack immunoglobulin A (IgA), a type...
hormone deficiency combined with common variable immunodeficiency and hypogammaglobulinemia. Semax, a synthetic analogue fragment of adrenocorticotropic hormone...
hormone deficiency combined with common variable immunodeficiency and hypogammaglobulinemia, which is caused by a heterozygous mutation in the NFKB2 gene. It...
multiple myeloma B-lineage cells. The most common side effects include hypogammaglobulinemia (low immunoglobulin or antibody levels in the blood, which increases...
disease is characterized by variable combination of enteropathy, hypogammaglobulinemia, recurrent respiratory infections, granulomatous lymphocytic interstitial...
that there is a risk of developing other autoimmune problems and hypogammaglobulinemia, in one cohort 58% of children with Evans syndrome had CD4-/CD8-...
thymus are associated with other autoimmune diseases – such as hypogammaglobulinemia, Graves disease, pure red cell aplasia, pernicious anaemia and dermatomyositis...
immunodeficiency, also known by the older name of common variable hypogammaglobulinemia (CVH) "Classic Van Halen", the iteration of the American rock band...
protein electrophoresis should be carried out. Reduced production (hypogammaglobulinemia), as well as increased protein loss (nephrotic syndrome, protein-losing...
infections, fatigue, musculoskeletal pain, and a weakened immune system (hypogammaglobulinemia). Idecabtagene vicleucel is a B-cell maturation antigen (BCMA)-directed...
effective antibodies drops below a threshold (a condition termed hypogammaglobulinemia), supplemental immunoglobulins may be provided by periodic infusions...
severity and persistence of infection in patients with AIDS and hypogammaglobulinemia indicates that both cell-mediated and humoral immunity are important...
isotypes. IgG deficiency is often found in children as transient hypogammaglobulinemia of infancy, which may occur with or without additional decreases...
lymphocytes, immunoglobulins, and proteins, causing lymphopenia, hypogammaglobulinemia, and hypoalbuminemia, respectively. The loss of proteins contributes...
Global Information