Hypercalciuria is the condition of elevated calcium in the urine. Chronic hypercalciuria may lead to impairment of renal function, nephrocalcinosis, and chronic kidney disease. Patients with hypercalciuria have kidneys that excrete higher levels of calcium than normal, for which there are many possible causes. Calcium may come from one of two paths: through the gut where higher than normal levels of calcium are absorbed by the body or mobilized from stores in the bones. After initial 24 hour urine calcium testing and additional lab testing, a bone density scan (DSX) may be performed to determine if the calcium is being obtained from the bones.
Hypercalciuria in patients can be due to underlying genetic causes.[1]
Signs and symptoms
There are no clinical signs or symptoms of hypercalciuria itself but elevated calcium in the urine can contribute to accelerated loss of calcium from bone leading to osteoporosis. Additionally, hypercalciuria can contribute to kidney stone formation which may present with flank or back pain that comes and goes. It can be painful to pass kidney stones and in extreme cases cause kidney damage.[2][3] Patients that both form kidney stones and have hypercalciuria are at increased risk for bone loss leading to osteoporosis.[4]
^"Hot Topic - Kidney Stones - Mayo Medical Laboratories". 2014-03-14. Archived from the original on 2014-03-14. Retrieved 2023-02-28.
^Contributors, WebMD Editorial. "What is a Calcium Urine Test?". WebMD. Retrieved 2023-02-28. {{cite web}}: |last= has generic name (help)
^"Idiopathic hypercalciuria: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2023-02-28.
^Ryan, Laura E.; Ing, Steven W. (2018-01-01). "Idiopathic hypercalciuria: Can we prevent stones and protect bones?". Cleveland Clinic Journal of Medicine. 85 (1): 47–54. doi:10.3949/ccjm.85a.16090. ISSN 0891-1150. PMID 29328898.
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(Ca) – per day 2.5 6.25 mmol / 24 h An abnormally high level is called hypercalciuria and an abnormally low rate is called hypocalciuria. 14637-3 100 250...
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