Medical condition caused by the deposition of calcium salts in the kidneys
Medical condition
Nephrocalcinosis
Other names
Anderson-Carr kidneys
Bilateral nephrocalcinosis seen on an abdominal x-ray
Specialty
Urology
Nephrocalcinosis, once known as Albright's calcinosis after Fuller Albright, is a term originally used to describe the deposition of poorly soluble calcium salts in the renal parenchyma due to hyperparathyroidism. The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate.[1] It may cause acute kidney injury. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification in radiology.[2] It is caused by multiple different conditions and is determined by progressive kidney dysfunction. These outlines eventually come together to form a dense mass.[3] During its early stages, nephrocalcinosis is visible on x-ray, and appears as a fine granular mottling over the renal outlines. It is most commonly seen as an incidental finding with medullary sponge kidney on an abdominal x-ray. It may be severe enough to cause (as well as be caused by) renal tubular acidosis or even end stage kidney disease, due to disruption of the kidney tissue by the deposited calcium salts.
^Sayer, John A.; Carr, Georgina; Simmons, Nicholas L. (June 2004). "Nephrocalcinosis: molecular insights into calcium precipitation within the kidney". Clinical Science. 106 (6): 549–561. doi:10.1042/CS20040048. ISSN 0143-5221. PMID 15027893.
conjunction with nephrocalcinosis, hypercalcaemia and hypercalciuria the following can occur: Primary hyperparathyroidism: Nephrocalcinosis is one of the...
(related to alkaline urine, hypercalciuria, and low urinary citrate). Nephrocalcinosis (deposition of calcium in the substance of the kidney) Bone demineralisation...
diaper syndrome Other names Other Names: Hypercalcemia, familial, with nephrocalcinosis and indicanuria Blue diaper syndrome has an autosomal recessive pattern...
excess amounts of calcium in the urine (hypercalciuria) and kidneys (nephrocalcinosis), which may lead to kidney stones. In rare occasions, the infant may...
Chronic hypercalciuria may lead to impairment of renal function, nephrocalcinosis, and chronic kidney disease. Patients with hypercalciuria have kidneys...
(elevated calcium in the urine) which may lead to kidney calcification (nephrocalcinosis) and chronic kidney disease. Calcium levels in the blood and urine...
Phosphate nephropathy or nephrocalcinosis is an adverse renal condition that arises with a formation of phosphate crystals within the kidney's tubules...
chains. Increased bone resorption leads to hypercalcemia and causes nephrocalcinosis, thereby contributing to kidney failure. Amyloidosis is a distant third...
cases of chronic disease. Symptomatic kidney involvement is usually nephrocalcinosis, although granulomatous interstitial nephritis that presents with reduced...
Amelogenesis imperfecta (AI) is a congenital disorder which presents with a rare abnormal formation of the enamel or external layer of the crown of teeth...
Konrad M (2000). "Familial hypomagnesaemia with hypercalciuria and nephrocalcinosis maps to chromosome 3q27 and is associated with mutations in the PCLN-1...
cystostomy may be considered for relief of obstructive urolithiasis. Nephrocalcinosis Kidney disease Kidney stone formation in space Schulsinger DA (2014)...
manifestation: about 25% of patients have evidence of nephrolithiasis or nephrocalcinosis. In contrast to sporadic cases of hyperparathyroidism, diffuse hyperplasia...
renal ultrasound can be done to assess for nephrolithiasis and/or nephrocalcinosis if there is concern for it. Differential diagnoses of hypercalcemia...
damage to endocrine organs. Common problems include hypercalcaemia and nephrocalcinosis (due to a lack of calcitonin from the thyroid), and pituitary problems...
ammonia excretion in freshwater and seawater fish: implications for nephrocalcinosis". Frontiers in Physiology. 14. doi:10.3389/fphys.2023.1226068. ISSN 1664-042X...
calcium, but this can further increase the risk for kidney stones and nephrocalcinosis Research has led to a better understanding of hypercalcemia in non-human...
calcium-containing kidney stones (also termed nephrolithiasis) and/or nephrocalcinosis (i.e., the deposition of calcium-containing material in multiple sites...
thrones and psychiatric overtones". "Stones" refers to kidney stones, nephrocalcinosis, and diabetes insipidus (polyuria and polydipsia). These can ultimately...
condition causes significant symptoms or if it affects the kidneys (nephrocalcinosis) or bone health (osteoporosis), and also in people under 50 even if...
(related to alkaline urine, hypercalciuria, and low urinary citrate). Nephrocalcinosis (deposition of calcium in the substance of the kidney) Bone demineralisation...
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