Primary hyperparathyroidism (or PHPT) is a medical condition where the parathyroid gland (or a benign tumor within it) produce excess amounts of parathyroid hormone (PTH). The symptoms of the condition relate to the resulting elevated serum calcium (hypercalcemia), which can cause digestive symptoms, kidney stones, psychiatric abnormalities, and bone disease.
The diagnosis is initially made on blood tests; an elevated level of calcium together with a raised (or inappropriately high) level of parathyroid hormone are typically found. To identify the source of the excessive hormone secretion, medical imaging may be performed. Parathyroidectomy, the surgical removal of one or more parathyroid glands, may be required to control symptoms.
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Primaryhyperparathyroidism (or PHPT) is a medical condition where the parathyroid gland (or a benign tumor within it) produce excess amounts of parathyroid...
parathyroid glands (primaryhyperparathyroidism) or as response to external stimuli (secondary hyperparathyroidism). Symptoms of hyperparathyroidism are caused...
developing tertiary hyperparathyroidism. Tertiary hyperparathyroidism was first described in the late 1960s and had been misdiagnosed as primary prior to this...
into "primaryhyperparathyroidism without cancer", "cancer without primaryhyperparathyroidism" as well as "combined primaryhyperparathyroidism and cancer"...
rhythm including cardiac arrest. Most outpatient cases are due to primaryhyperparathyroidism and inpatient cases due to cancer. Other causes of hypercalcemia...
all documented cases of hyperparathyroidism. Hereditary factors Approximately 1 in 10 documented cases of hyperparathyroidism are a result of hereditary...
Sensipar among others, is a medication used to treat primaryhyperparathyroidism, tertiary hyperparathyroidism and parathyroid carcinoma. Cinacalcet acts as...
processes lead to hypocalcemia and hence secondary hyperparathyroidism. Secondary hyperparathyroidism can also result from malabsorption (chronic pancreatitis...
This is called hyperparathyroidism; it leads to hypercalcemia, kidney stones, osteoporosis, and various other symptoms. Hyperparathyroidism was first described...
circumstances. Primaryhyperparathyroidism is due to autonomous, abnormal hypersecretion of PTH from the parathyroid gland, while secondary hyperparathyroidism is...
metastasis (with or without hypercalcemia), multiple myeloma, primaryhyperparathyroidism, osteogenesis imperfecta, fibrous dysplasia, and other conditions...
parathyroid hormone. This is known as secondary hyperparathyroidism. If secondary hyperparathyroidism persists over months, the parathyroid tissue may...
or primaryhyperparathyroidism may be the initial diagnosis.[citation needed] Pheochromocytoma occurs in 33-50% of MEN2 cases. In MEN2A, primary hyperparathyroidism...
parathyroid tissue. The main indication for parathyroidectomy is primaryhyperparathyroidism, a condition in which one or more of the parathyroid glands produce...
patellas (trick knee), epilepsy, Cushing's disease, diabetes, primaryhyperparathyroidism, and hypothyroidism. Von Willebrand's disease has been known...
sestamibi scanning. The natural distribution of causation for primaryhyperparathyroidism is roughly 85% solitary adenomas, 10-15% diffuse hyperplasia...
blood, including people with milk-alkali syndrome, sarcoidosis, primaryhyperparathyroidism, and hypervitaminosis D. In rare cases, certain medications such...
level above the reference range) is mostly caused by either primaryhyperparathyroidism or malignancy, and therefore, it is reasonable to include these...
Retrieved March 24, 2021. Insogna, Karl (September 13, 2018). "PrimaryHyperparathyroidism". New England Journal of Medicine. 379 (11): 1050–1059. doi:10...
inappropriately high amounts of parathyroid hormone and thereby cause primaryhyperparathyroidism. Hepatic adenomas are a rare benign tumour of the liver, which...
generally causes hyperparathyroidism; there are very few reports of parathyroid adenomas that were not associated with hyperparathyroidism. A human being...
procedures, such as Echocardiography or Cardiac MRI. Cardiomegaly Primaryhyperparathyroidism Ventricular hypertrophy Maron BJ, Maron MS (January 2013). "Hypertrophic...
following can occur: Primaryhyperparathyroidism: Nephrocalcinosis is one of the most common symptoms of primaryhyperparathyroidism. Sarcoidosis: Nephrocalcinosis...
lesion that arises in settings of excess osteoclast activity, such as hyperparathyroidism. They are a form of osteitis fibrosa cystica. It is not a neoplasm...