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Hygrine information


Hygrine
Chemical structure of hygrine
Ball-and-stick model of hygrine molecule
Names
Preferred IUPAC name
1-[(2R)-1-Methylpyrrolidin-2-yl]propan-2-one
Identifiers
CAS Number
  • 496-49-1 checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:46750 checkY
ChemSpider
  • 389762 checkY
ECHA InfoCard 100.007.112 Edit this at Wikidata
KEGG
  • C06179 checkY
PubChem CID
  • 440933
UNII
  • 49H1LNM62X checkY
CompTox Dashboard (EPA)
  • DTXSID40894081 Edit this at Wikidata
InChI
  • InChI=1S/C8H15NO/c1-7(10)6-8-4-3-5-9(8)2/h8H,3-6H2,1-2H3/t8-/m1/s1 checkY
    Key: ADKXZIOQKHHDNQ-MRVPVSSYSA-N checkY
  • InChI=1/C8H15NO/c1-7(10)6-8-4-3-5-9(8)2/h8H,3-6H2,1-2H3/t8-/m1/s1
    Key: ADKXZIOQKHHDNQ-MRVPVSSYBT
SMILES
  • CC(=O)C[C@H]1CCCN1C
Properties
Chemical formula
C8H15NO
Molar mass 141.21 g/mol
Boiling point 193 to 195 °C (379 to 383 °F; 466 to 468 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

Hygrine is a pyrrolidine alkaloid, found mainly in coca leaves (0.2%). It was first isolated by Carl Liebermann in 1889 (along with a related compound cuscohygrine) as an alkaloid accompanying cocaine in coca. Hygrine is extracted as a thick yellow oil, having a pungent taste and odor.

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Hygrine

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Hygrine is a pyrrolidine alkaloid, found mainly in coca leaves (0.2%). It was first isolated by Carl Liebermann in 1889 (along with a related compound...

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Hyoscyamine

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with acetoacetic acid yielding hygrine. No enzymatic activity could be demonstrated that catalyzes this reaction. Hygrine further rearranges to tropinone...

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Cuscohygrine

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pyrrolinium salt with acetoacetyl coenzyme A yields hygrine. Finally, the condensation of the hygrine molecule with another molecule of pyrrolidinium salt...

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Benzoylecgonine

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have a negative ecological impact. Coca alkaloids Dihydrocuscohygrine Hygrine Schindler, Charles W; Goldberg, Steven R (2012). "Accelerating cocaine...

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Pyrrolidine

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ring structure is present in numerous natural alkaloids i.a. nicotine and hygrine. It is found in many drugs such as procyclidine and bepridil. It also forms...

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Scopolamine

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with acetoacetic acid yielding hygrine. No enzymatic activity could be demonstrated to catalyze this reaction. Hygrine further rearranges to tropinone...

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Coca alkaloid

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Methylecgonine cinnamate Tropacocaine Truxilline Cuscohygrine Dihydrocuscohygrine Hygrine Nicotine Cocaine metabolites (Human) Coca wine, an alcoholic beverage combining...

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Alkaloid

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putrescine → N-methylputrescine → N-methyl-Δ1-pyrroline Cuscohygrine, hygrine, hygroline, stachydrine Tropane derivatives Atropine group Substitution...

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Methylecgonine cinnamate

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chewing of coca leaves and abuse of cocaine by hair analysis including hygrine, cuscohygrine, cinnamoylcocaine and cocaine metabolite/cocaine ratios"...

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Anisochilus

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has active properties such as camphor, leutiolin, and apigenin. A new hygrine-like compound has been found within the DNA of this plant. Species Anisochilus...

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Catuabine

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which is an active constituent of another species, Erythroxylum coca. Hygrine Cuscohygrine Glasl, S.; Presser, A.; Werner, I.; Haslinger, E.; Jurenitsch...

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C8H15NO

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exact mass: 141.1154 u) may refer to: 3,3-Diethyl-2-pyrrolidinone (DEABL) Hygrine Pseudotropine (PTO) Tropine This set index page lists chemical structure...

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Coca

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hydroxytropacocaine, tropacocaine, ecgonine, cuscohygrine, dihydrocuscohygrine, and hygrine. When chewed, coca acts as a mild stimulant and suppresses hunger, thirst...

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Biosynthesis of cocaine

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in cocaine, the N-methyl-pyrrolinium cation is a precursor to nicotine, hygrine, cuscohygrine, and other natural products. The additional carbon atoms...

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Pyrrolidine alkaloids

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norruspolinone and norruspoline also belong to this alkaloid group. (+)-Hygrine (-)-Codonopsinine (-)-Ruspolinone (R)-Norruspoline Many plants containing...

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Nicandra physalodes

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presence of the tropane alkaloid tropinone and the pyrrolidine alkaloid hygrine (0.1%, in the root). Withanolides are found almost exclusively in plants...

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List of compounds with carbon number 8

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13618-93-4 C8H15N octanenitrile 124-12-9 C8H15N tropane 529-17-9 C8H15NO hygrine 496-49-1 C8H15NO tropine 120-29-6 C8H15NO2 cyclopentanecarboxylic acid...

Word Count : 28

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