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History of apoptosis research information


Apoptosis is the process of programmed cell death. From its early conceptual beginnings in the 1950s, it has exploded as an area of research within the life sciences community. As well as its implication in many diseases, it is an integral part of biological development.

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History of apoptosis research

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Apoptosis is the process of programmed cell death. From its early conceptual beginnings in the 1950s, it has exploded as an area of research within the...

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Apoptosis

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Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms...

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Programmed cell death

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to apoptosis when the apoptosis signaling is blocked by endogenous or exogenous factors such as viruses or mutations. Most recently, other types of regulated...

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Herpes simplex research

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replication process. This causes the cell to die via apoptosis. Apoptosis is regulated with the help of miRNAs, which are small non-coding RNAs that negatively...

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Philadelphia chromosome

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to DNA damage and promotes apoptosis in normal cells. The BCR-ABL fusion, in contrast, has been shown to inhibit apoptosis, but its effect on DNA binding...

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Scientific research on the International Space Station

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Effects of Microgravity on the Haemopoietic System: A Study on Neocytolysis (Neocytolysis) PAthway DIfferent ACtivators (PADIAC) ROle of Apoptosis in Lymphocyte...

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History of pathology

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The history of pathology can be traced to the earliest application of the scientific method to the field of medicine, a development which occurred in...

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Sanford Burnham Prebys Medical Discovery Institute

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cells deprived of attachment to extracellular matrix commit suicide by apoptosis, named Anoikis, connected the cell adhesion and apoptosis fields. These...

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HIV

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leads to low levels of CD4+ T cells through a number of mechanisms, including pyroptosis of abortively infected T cells, apoptosis of uninfected bystander...

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Cell division

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activating the p53 upregulated modulator of apoptosis (PUMA). PUMA is a pro-apoptotic protein that rapidly induces apoptosis by inhibiting the anti-apoptotic...

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Arabic

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coin new words using forms within existing roots (استماتة istimātah 'apoptosis', using the root موت m/w/t 'death' put into the Xth form, or جامعة jāmiʻah...

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Embryonic stem cell

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damage. Rather they undergo programmed cell death (apoptosis) in response to DNA damage. Apoptosis can be used as a fail-safe strategy to remove cells...

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The Hallmarks of Cancer

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thus apoptosis cannot activate. They may also have defects in the downstream signaling itself, or the proteins involved in apoptosis, each of which will...

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Sperm

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with age. Also apoptosis decreases with age suggesting that the increase in damaged DNA of sperm as men age occurs partly as a result of less efficient...

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HeLa

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research involving fullerenes to induce apoptosis as a part of photodynamic therapy, as well as in in vitro cancer research using cell lines. HeLa cells have...

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Tumor suppressor gene

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regulate cell growth by either inhibiting cell cycle progression or inducing apoptosis. Lastly landscaper genes regulate growth by contributing to the surrounding...

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Egg cell

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the oocytes. This transfer is followed by the programmed cell death (apoptosis) of the nurse cells. During oogenesis, 15 nurse cells die for every oocyte...

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Cellular anastasis

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assumption that apoptosis is irreversible, some cells resist the stimuli that trigger apoptosis and can survive even following the activation of executioner...

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Apoptotic DNA fragmentation

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during apoptosis, although they do exhibit some other features of apoptosis and die. Even though much work has been performed on the analysis of apoptotic...

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Influenza

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Counter-Response, and Apoptosis". Viruses. 9 (8): 223. doi:10.3390/v9080223. PMC 5580480. PMID 28805681. Hao W, Wang L, Li S (October 2020). "Roles of the Non-Structural...

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List of Equinox episodes

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influx of citizens from less-wealthy continents, as well as a likely pensions crisis; Osiris Therapeutics; apoptosis and Ian Judson, and trials of imatinib...

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Mathematical and theoretical biology

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modelling of the cell cycle Mathematical modelling of apoptosis Modelling physiological systems Modelling of arterial disease Multi-scale modelling of the heart...

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