Hepatic fructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate.
ATP + ADP +
ATP + D-fructose → ADP + D-fructose-1-phosphate[1]
^Bais R, James HM, Rofe AM, Conyers RA (1985). "The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol". Biochem. J. 230 (1): 53–60. doi:10.1042/bj2300053. PMC 1152585. PMID 2996495.
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Hepaticfructokinase (or ketohexokinase) is an enzyme that catalyzes the phosphorylation of fructose to produce fructose-1-phosphate. ATP + ⟶ {\displaystyle...
diagnosis of fructosuria are hepaticfructokinase deficiency, levulosuria and ketohexokinase deficiency. Hepaticfructokinase PFKL PFKM PFKP Glucokinase...
Essential fructosuria, caused by a deficiency of the enzyme hepaticfructokinase, is a clinically benign condition characterized by the incomplete metabolism...
encoding hepaticfructokinase, an enzyme that catalyzes the first step in the metabolism of dietary fructose. Inactivation of the hepaticfructokinase results...
liver by fructokinase (Km= 0.5 mM) and galactokinase (Km = 0.8 mM), respectively. By contrast, glucose tends to pass through the liver (Km of hepatic glucokinase...
fructose is the phosphorylation of fructose to fructose 1-phosphate by fructokinase (Km = 0.5 mM, ≈ 9 mg/100 ml), thus trapping fructose for metabolism in...
concentration rises, it serves as a central metabolic switch to shift hepatic carbohydrate metabolism between fed and fasting states. Phosphorylation...
family described here bears a resemblance to the ATP-driven phospho-fructokinases; however, they share little sequence similarity, although a few residues...
as the RK family) include ribokinase (RK), inosine-guanosine kinase, fructokinase, and 1-phosphofructokinase. The members of the PfkB/RK family are identified...
intestinal mucosa. When fructose is absorbed, it is phosphorylated by fructokinase to form fructose 1-phosphate. Aldolase B then catalyzes F1P breakdown...