regulation of alternative mRNA splicing, via spliceosome
RNA metabolic process
cellular response to glucose starvation
transport
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
3178
15382
Ensembl
ENSG00000135486
ENSMUSG00000046434
UniProt
P09651
P49312
RefSeq (mRNA)
NM_002136 NM_031157
NM_001039129 NM_010447
RefSeq (protein)
NP_002127 NP_112420
NP_001034218 NP_034577
Location (UCSC)
n/a
Chr 15: 103.15 – 103.16 Mb
PubMed search
[2]
[3]
Wikidata
View/Edit Human
View/Edit Mouse
Heterogeneous nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the HNRNPA1 gene.[4] Mutations in hnRNP A1 are causative of amyotrophic lateral sclerosis and the syndrome multisystem proteinopathy.
^ abcGRCm38: Ensembl release 89: ENSMUSG00000046434 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Saccone S, Biamonti G, Maugeri S, Bassi MT, Bunone G, Riva S, Della Valle G (Mar 1992). "Assignment of the human heterogeneous nuclear ribonucleoprotein A1 gene (HNRPA1) to chromosome 12q13.1 by cDNA competitive in situ hybridization". Genomics. 12 (1): 171–4. doi:10.1016/0888-7543(92)90424-Q. PMID 1733858.
nuclear ribonucleoprotein A1 is a protein that in humans is encoded by the HNRNPA1 gene. Mutations in hnRNP A1 are causative of amyotrophic lateral sclerosis...
PKM gene is regulated through heterogenous ribonucleotide proteins like hnRNPA1 and hnRNPA2. Human PKM2 monomer has 531 amino acids and is a single chain...
ubiquitin-positive cytoplasmic inclusions of RNA-binding proteins, such as TDP-43, HNRNPA1, HNRNPA2B1, and other components of RNA granules. MSP is a dominantly inherited...
prion-like domains of heterogeneous nuclear riboproteins hnRNPA2B1 and hnRNPA1 in familial cases of muscle, brain, bone and motor neuron degeneration...
length of intron/exon organization of HNRNPA2B1 is identical to that of the HNRNPA1 gene which indicates a common origin by gene duplication. This gene belongs...
structure of Intronic splicing silencer and its interaction to host protein hnRNPA1 give insight into specific recognition. However, adding to the complexity...
phase separating and aggregation-prone proteins include FUS, TDP-43 and hnRNPA1. Aggregates of these proteins are associated with neurodegenerative diseases...
an autosomal dominant condition caused by mutations in VCP, HNRPA2B1 or HNRNPA1; it is a multisystem degenerative disorder that can affect muscle, bone...
repressors are heterogeneous nuclear ribonucleoproteins (hnRNPs) such as hnRNPA1 and polypyrimidine tract binding protein (PTB). Splicing enhancers are...
for 1% of fALS and less than 1% of sALS. PFN1 was identified in 2012, HNRNPA1 and HNRNPA2B1 in 2013, CHCHD10, MATR3, and TUBA4A in 2014, and TBK1 in...
Hay DC, Kemp GD, Dargemont C, Hay RT (May 2001). "Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent...
Hay DC, Kemp GD, Dargemont C, Hay RT (May 2001). "Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent...
Japanese population by whole-exome sequencing and identification of novel HNRNPA1 mutation". Neurobiology of Aging. 61: 255.e9–255.e16. doi:10.1016/j.neurobiolaging...
Hay DC, Kemp GD, Dargemont C, Hay RT (May 2001). "Interaction between hnRNPA1 and IkappaBalpha is required for maximal activation of NF-kappaB-dependent...
prostate cancer cells proliferation. In addition, Sam68 in conjunction with hnRNPA1 influences the choice of the alternative 5' splice sites of Bcl-x regulating...
described for this gene. BAT2 has been shown to interact with: C1QBP, EIF3S6, HNRNPA1, IFT88, IMMT, and UBAP2L. ENSG00000206427, ENSG00000231825, ENSG00000231370...
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