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HBsAg information


Large envelope protein
Identifiers
OrganismHepatitis B virus genotype B2 (isolate Vietnam/9873/1997)
SymbolS
UniProtQ9QAB7
Search for
StructuresSwiss-model
DomainsInterPro
The genome organisation of HBV; the genes overlap. ORF S, in green, encodes HBsAg.
HBsAg under a transmission electron microscope: the protein self assembles into virus-like particles

HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). Its presence in blood indicates existing hepatitis B infection.

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HBsAg

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HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). Its presence in blood indicates existing hepatitis...

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Hepatitis B

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removal of the HBsAg and the appearance of anti-HBs is called the window period. A person negative for HBsAg but positive for anti-HBs either has cleared...

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Hepatitis B vaccine

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people receiving chemotherapy; and for sexual partners of HBsAg-positive people. An anti-Hbs antibody level above 100 mIU/ml is deemed adequate, and occurs...

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Window period

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during HBsAg to HBsAb seroconversion, i.e. between the disappearance of surface antigen (HBsAg) from serum and the appearance of HBsAb (anti-HBs), and...

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Hepatitis

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antigen (anti-HBcAg) can differentiate between acute and chronic infection. People who are high-risk whose blood tests negative for HBsAg can receive the...

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Epidemiology of hepatitis D

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it shares the HBsAg coat; in superinfections of HBsAg carriers, it is rescued by the foreign HBV of the carrier which provides the HBsAg coat for the assembly...

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Nitazoxanide

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in undetectable HBV DNA, loss of HBeAg and loss of HBsAg. These preliminary studies showed a higher rate of HBsAg loss than any currently licensed therapy...

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Ortho Clinical Diagnostics

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The New York Times. "Vitros Immunodiagnostic Products HBsAg Reagent Pack and Calibrator, and HBsAg Confirmatory Kit - P000044". www.fda.gov. Archived from...

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HBeAg

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expression. HBeAg is dispensable for replication, as mutant viruses with defects in the pre-C region are both infectious and pathogenic. HBcAg HBsAg Suslov,...

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Seroconversion

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infection. The window period for HBsAg/anti-HBs testing occurs as concentration of HBsAg falls and before the body develops anti-HBs antibodies, lasting approximately...

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Hepatitis B virus

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called the surface antigen (HBsAg), and is produced in excess during the life cycle of the virus. It consists of: HBsAg (hepatitis B surface antigen)...

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Polyarteritis nodosa

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30% of people with PAN have chronic hepatitis B and deposits containing HBsAg-HBsAb complexes in affected blood vessels, indicating an immune complex-mediated...

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Hepatitis B immune globulin

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development of hepatitis B and is used for the treatment of acute exposure to HBsAg. HBIG is indicated as a postexposure prophylaxis for people at risk to develop...

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Hepatitis D

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receptor via the N-terminal domain of the large hepatitis B surface antigen, HBsAg. Mapping by mutagenesis of this domain has shown that amino acid residues...

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Hepatitis B virus precore mutant

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"major" envelope protein (HBsAg). The largest gene is P. It codes for DNA polymerase. The C gene codes for HBeAg and HBcAg. The C gene has a precore and...

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Liver disease

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Hepatitis B virus is present by hepatitis B virus DNA, but testing for HBsAg is negative. High consumption of alcohol can lead to several forms of liver...

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HBcAg

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HBeAg HBsAg Kimura T, Rokuhara A, Matsumoto A, et al. (May 2003). "New enzyme immunoassay for detection of hepatitis B virus core antigen (HBcAg) and...

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Malaria vaccine

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proportion than the RTS,S vaccine. It uses the same HBsAg-linked recombinant structure, but contains no excess HBsAg. It includes the Matrix-M adjuvant that is...

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Subunit vaccine

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immunogenicity. Regarding application, both the hepatitis B virus surface antigen (HBsAg) and the virus-like particles (VLPs) of the major capsid protein L1 of human...

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BLOSUM

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among hepatitis B virus carriers and T-cell epitopes. DNA sequences of HBsAg were obtained from 180 patients, in which 51 were chronic HBV carrier and...

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Obstetrics

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Rapid plasma reagin test to screen for syphilis Rubella antibody screen HBsAg test to screen for hepatitis B Testing for chlamydia (and gonorrhea when...

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Hep G2

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Plotkin S, Damjanov I, Knowles BB (December 1979). "Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line". Nature. 282...

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Edible vaccine

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had some form of an immune response, and 62.5% showed an increase in anti-HBsAg titers. From these studies, the National Institute of Allergy and Infectious...

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Helper dependent virus

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because it requires Hepatitis B virus (HBV) to provide HBV surface antigen (HBsAg) for the encapsidation of its genome. The envelope proteins on the outer...

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Irving Millman

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the virus. The coating, hepatitis B surface antigen (HBsAg), is not infectious; however, HBsAG can provoke an immune response. In order to develop a...

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