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HBeAg information


A simplified drawing of the HBV particle and surface antigen. Purple = Lipid Envelope, Red = Nucleocapsid Core (Note: This drawing is slightly misleading in that the nucleocapsid core is a single entity even though it is depicted as a light blue icosahedral line shape and a red ring of circles).
The genome organisation of HBV. The genes overlap. (ORF Core, at bottom left, encodes HBcAg; when translated together with Pre C, it produces soluble HBeAg.)

HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication; this means the person infected with Hepatitis B can likely transmit the virus on to another person (i.e. the person is infectious). HBeAg is considered a marker for cccDNA replication.[1]

  1. ^ Suslov, A.; Meier, M. A.; Ketterer, S.; Wang, X.; Wieland, S.; Heim, M. H. (2021). "Transition to HBeAg-negative chronic hepatitis B virus infection is associated with reduced cccDNA transcriptional activity". Journal of Hepatology. 74 (4): 794–800. doi:10.1016/j.jhep.2020.11.003. PMID 33188905. S2CID 226961485.

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HBeAg

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HBeAg is a hepatitis B viral protein, produced by the HBcAg reading frame. It is an indicator of active viral replication; this means the person infected...

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Hepatitis B

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During the natural course of an infection, the HBeAg may be cleared, and antibodies to the 'e' antigen (anti-HBe) will arise immediately afterwards. This conversion...

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HBcAg

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hepatitis B virus). While both HBcAg and HBeAg are made from the same open reading frame, HBcAg is not secreted. HBcAg is considered "particulate" and it does...

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HBsAg

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from HBsAg extracted from the blood plasma of hepatitis patients. More modern vaccines are made from recombinant HBsAg grown in yeast. HBcAg HBeAg Guarascio...

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Hepatitis B virus precore mutant

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region, the protein product is HBeAg. If translation begins with the core region, HBcAg is the protein product. HBeAg is a marker of HBV replication and...

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Hepatitis B virus

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considered "nonparticulate" and is secreted and accumulates in serum. HBeAg and HBcAg are made from the same reading frame. HBx is small, 154 amino acids...

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Nitazoxanide

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DNA in all of 4 HBeAg-positive patients, with undetectable HBV DNA in 2 of 4 patients, loss of HBeAg in 3 patients, and loss of HBsAg in one patient....

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Seroconversion

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Seroreversion from HBeAg is thus used as one marker of resolution of infection. On a serological assay, the presence of hepatitis B surface antigen (HBsAg) indicates...

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Entecavir

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replication in vitro Superior activity compared to LVD in vivo for both HBeAg+ & HBeAg− patients Efficacy in LVD refractory CHB patients Entecavir was approved...

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Hepatitis

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approximately 10–20% when maternal blood is positive for HBsAg, and up to 90% when also positive for HBeAg. Given the high risk of perinatal transmission, the...

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Viral hepatitis

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Hepeviridae Genome (+)ssRNA dsDNA-RT (+)ssRNA (−)ssRNA (+)ssRNA Antigens HBsAg, HBeAg Core antigen Delta antigen Transmission Enteral Parenteral Parenteral...

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Hepadnaviridae

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viral polymerase, surface antigens—preS1, preS2, and S, the X protein and HBeAg. The X protein is thought to be non-structural. Its function and significance...

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P24 capsid protein

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original on 9 March 2008. "Frequently Asked Questions: Fourth Generation HIV Ab/Ag Combination Assays" (PDF). PA/ MidAtlantic AIDS Education and Training Center...

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George Lau

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Peginterferon Alfa-2a HBeAg-Positive Chronic Hepatitis B Study Group. Peginterferon Alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis...

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Hepatitis B in China

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"Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial". The Lancet. 365 (9454):...

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Transmission of hepadnaviruses

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South and East Asia and sub-Saharan Africa. In some cases breast milk of HBsAg positive mothers has been found to be positive for the virus, but there have...

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VP40

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VSPs: HBsAg HBcAg HBeAg VNPs: HBx Hepatitis B virus DNA polymerase...

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Zeynel Mungan

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Okten A. What is the reason of elevated alanine aminotransferase level in HBeAg negative patients with low viremia: NAFLD or chronic hepatitis? Ann Hepatol...

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Clevudine

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12-week clevudine therapy showed potent and durable antiviral activity in HBeAg-positive chronic hepatitis B". Hepatology. 43 (5): 982–8. doi:10.1002/hep...

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Visa requirements for Indian citizens

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eVisa". "Visa on Arrival | Immigration Antigua and Barbuda". Immigration.gov.ag. 21 June 2016. Retrieved 6 March 2022. Visa regime, National Directorate of...

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List of official business registers

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Retrieved 7 July 2018. "BREG Online Services - powered by eHawaii.gov". hbe.ehawaii.gov. Retrieved 7 July 2018. "IDSOS Search for Business Entities"...

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List of mineral symbols

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Häggite Hgg Hawthorneite Hwt Hereroite Hre Hochelagaite Haga Humberstonite Hbe Hydroxykenomicrolite Hykmic Hagstromite Hgs Haxonite Hax Hermannjahnite Hjh...

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List of astronomy acronyms

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with strong spectral emission lines HAe – (celestial object) Herbig Ae star HBe – (celestial object) Herbig Be star HALCA – (telescope) Highly Advanced Laboratory...

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Argon compounds

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barrier to decomposition that it will likely never be observed. However HBeArF is predicted to be more stable than HArF. CUO in a solid argon matrix...

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Helium compounds

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are HNaHe+ sodium hydrohelide cation, HKHe+ potassium hydrohelide cation, HBeHe2+ beryllium hydrohelide cation, HMgHe2+ magnesium hydrohelide cation, and...

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List of preserved steam locomotives in Germany

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G 7.1 engines were built from 1893 by the firm of Stettiner Maschinenbau AG Vulcan. They were equipped with the same boiler as that of the Prussian G...

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