positive regulation of macrophage derived foam cell differentiation
cellular response to prostaglandin stimulus
response to virus
positive regulation of lipid storage
cellular response to tumor necrosis factor
response to selenium ion
flagellated sperm motility
positive regulation of gene expression
response to organic substance
cholesterol homeostasis
spermatogenesis
triglyceride catabolic process
cholesterol efflux
post-embryonic development
lipoprotein transport
toll-like receptor signaling pathway
response to estradiol
membrane organization
chylomicron remodeling
low-density lipoprotein particle remodeling
chylomicron assembly
very-low-density lipoprotein particle assembly
chylomicron remnant clearance
low-density lipoprotein particle clearance
very-low-density lipoprotein particle clearance
lipoprotein metabolic process
lipoprotein biosynthetic process
lipoprotein catabolic process
post-translational protein modification
transport
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
338
238055
Ensembl
ENSG00000084674
ENSMUSG00000020609
UniProt
P04114
E9Q414
RefSeq (mRNA)
NM_000384
NM_009693
RefSeq (protein)
NP_000375
NP_033823
Location (UCSC)
Chr 2: 21 – 21.04 Mb
Chr 12: 8.03 – 8.07 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Apolipoprotein B (ApoB) is a protein that in humans is encoded by the APOB gene. It is commonly used to detect risk of atherosclerotic cardiovascular disease.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000084674 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000020609 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Glavinovic T, Thanassoulis G, de Graaf J, Couture P, Hegele RA, Sniderman AD (October 2022). "Physiological Bases for the Superiority of Apolipoprotein B Over Low-Density Lipoprotein Cholesterol and Non-High-Density Lipoprotein Cholesterol as a Marker of Cardiovascular Risk". Journal of the American Heart Association. 11 (20): e025858. doi:10.1161/JAHA.122.025858. PMC 9673669. PMID 36216435.
^Behbodikhah J, Ahmed S, Elyasi A, Kasselman LJ, De Leon J, Glass AD, Reiss AB (October 2021). "Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target". Metabolites. 11 (10): 690. doi:10.3390/metabo11100690. PMC 8540246. PMID 34677405.
ApolipoproteinB (ApoB) is a protein that in humans is encoded by the APOB gene. It is commonly used to detect risk of atherosclerotic cardiovascular disease...
Apolipoproteins are proteins that bind lipids (oil-soluble substances such as fats, cholesterol and fat soluble vitamins) to form lipoproteins. They transport...
Apolipoprotein E (Apo-E) is a protein involved in the metabolism of fats in the body of mammals. A subtype is implicated in Alzheimer's disease and cardiovascular...
receptor protein, which normally removes LDL from the circulation, or apolipoproteinB (ApoB), which is the part of LDL that binds with the receptor; mutations...
Apolipoprotein AI (Apo-AI) is a protein that in humans is encoded by the APOA1 gene. As the major component of HDL particles, it has a specific role in...
upon apolipoproteinB-100. In the blood stream, nascent VLDL particles bump with HDL particles; as a result, HDL particles donate apolipoprotein C-II...
ApolipoproteinB deficiency is an autosomal dominant disorder resulting from a missense mutation which reduces the affinity of apoB-100 for the low-density...
dense cholesterol transport particles, contain apolipoproteinB-48, apolipoprotein C, and apolipoprotein E (the principal cholesterol carrier in the brain)...
I-like lipid antigen presenting molecule. ApolipoproteinB can exist in two forms: B-100 and B-48. ApolipoproteinB-100 is present on several lipoproteins...
ApolipoproteinB mRNA editing enzyme, catalytic polypeptide 1 also known as C->U-editing enzyme APOBEC-1 is a protein that in humans is encoded by the...
diseases. A Mediterranean diet is recommended as a means of lowering ApolipoproteinB. The Mediterranean diet is low in saturated fat with high amounts of...
cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoproteinB: a systematic review and meta-analysis of randomized controlled trials"...
APOBEC ("apolipoproteinB mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases. A mechanism of generating...
triglyceride transfer protein resulting in deficiencies in the apolipoproteinsB-48 and B-100, which are used in the synthesis and exportation of chylomicrons...
cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoproteinB: a systematic review and meta-analysis of randomized controlled trials"...
with placebo, it decreased concentrations of LDL-C (by up to 51%), apolipoproteinB (by up to 30%) and non-high-density lipoprotein cholesterol (non-HDL-C)...
; Wayne, R.K.; Springer, M.S. (2003). "A new phylogenetic marker, apolipoproteinB, provides compelling evidence for eutherian relationships". Molecular...
cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoproteinB: a systematic review and meta-analysis of randomized controlled trials"...
Robert K.; Springer, Mark S. (2003). "A new phylogenetic marker, apolipoproteinB, provides compelling evidence for eutherian relationships". Molecular...
large lipid transfer protein family, like apolipoproteinB (apo B), with which it interacts, but unlike apo B, it is not secreted. The heterodimer is instead...
Apolipoprotein D (ApoD) is a protein that in humans is encoded by the APOD gene. Unlike other lipoproteins, which are mainly produced in the liver, apolipoprotein...
particular cause of acanthocytosis (also known as abetalipoproteinemia, apolipoproteinB deficiency, and Bassen-Kornzweig syndrome) is a rare, genetically inherited...
kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoproteinB lipoproteins through both low-density lipoprotein receptor-dependent...
been described. Mipomersen binds to the messenger RNA coding for apolipoproteinB-100 (ApoB-100), a protein that is the main component of low-density lipoprotein...
; Wayne, R.K.; Springer, M.S. (2003). "A new phylogenetic marker, apolipoproteinB, provides compelling evidence for eutherian relationships". Molecular...
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