For bioinformatics databases, see List of biological databases.
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Gene Disease Database
Classification
Bioinformatics
Subclassification
Databases
Type of Databases
Biological
Subtype of Databases
Gene-Disease
In bioinformatics, a Gene Disease Database is a systematized collection of data, typically structured to model aspects of reality, in a way to comprehend the underlying mechanisms of complex diseases, by understanding multiple composite interactions between phenotype-genotype relationships and gene-disease mechanisms.[1] Gene Disease Databases integrate human gene-disease associations from various expert curated databases and text mining derived associations including Mendelian, complex and environmental diseases.[2][3]
^A. Bauer-Mehren, "Gene-Disease network Analysis Reveals Functional Modules in Mendelian, Complex and Environmental diseases," PLOS One, pp. 1-3, 2011.
^Botstein, D (2003). "Discovering genotypes underlying human phenotypes: past successes for Mendelian disease, future approaches for complex disease". Nature Genetics. 33 (1): 228–237. doi:10.1038/ng1090. PMID 12610532. S2CID 10599219.
^Wren JD, Bateman A (2008). "Databases, data tombs and dust in the wind". Bioinformatics. 24 (19): 2127–8. doi:10.1093/bioinformatics/btn464. PMID 18819940.
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