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Biological database information


Home page of a biological database called STRING which characterises functional links between proteins.[1]

Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis.[citation needed] They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics.[2] Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures.

Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.)

Databases are important tools in assisting scientists to analyze and explain a host of biological phenomena from the structure of biomolecules and their interaction, to the whole metabolism of organisms and to understanding the evolution of species. This knowledge helps facilitate the fight against diseases, assists in the development of medications, predicting certain genetic diseases and in discovering basic relationships among species in the history of life.

  1. ^ Szklarczyk D; Franceschini A; Kuhn M; et al. (January 2011). "The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored". Nucleic Acids Res. 39 (Database issue): D561–8. doi:10.1093/nar/gkq973. PMC 3013807. PMID 21045058.
  2. ^ Altman RB (March 2004). "Building successful biological databases". Brief. Bioinformatics. 5 (1): 4–5. doi:10.1093/bib/5.1.4. PMID 15153301.

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Biological database

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lists of databases or databanks: List of academic databases and search engines List of biodiversity databases List of biological databases List of chemical...

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Sequence database

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Biological data

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characterized as biological data. Biological data is highly complex when compared with other forms of data. There are many forms of biological data, including...

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Protein structure database

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structures, providing the biological community access to the experimental data in a useful way. Data included in protein structure databases often includes three-dimensional...

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DNA database

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Data curation

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to be converted into an electronic format, such as an entry of a biological database. In the modern era of big data, the curation of data has become more...

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Pseudomonas Genome Database

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DNA Data Bank of Japan

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ZINC database

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capabilities. The database contents are continuously updated. PubChem a database of small molecules from the chemical and biological literature, hosted...

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CATH database

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The CATH Protein Structure Classification database is a free, publicly available online resource that provides information on the evolutionary relationships...

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Crystallography Open Database

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Crystallography Open Database (COD) is a database of crystal structures. Unlike similar crystallography databases, the database is entirely open-access...

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ClinVar

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between human variations and phenotypes, with supporting evidence. The database includes germline and somatic variants of any size, type or genomic location...

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Synthetic Gene Database

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The Synthetic Gene Database (SGDB) is a database of artificially engineered genes. Gene Wu, Gang; Zheng Yuanpu; Qureshi Imran; Zin Htar Thant; Beck Tyler;...

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