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Formaldehyde dehydrogenase information


formaldehyde dehydrogenase
Formaldehyde dehydrogenase homotetramer, Pseudomonas putida
Identifiers
EC no.1.2.1.46
CAS no.9028-84-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a formaldehyde dehydrogenase (EC 1.2.1.46) is an enzyme that catalyzes the chemical reaction

formaldehyde + NAD+ + H2O formate + NADH + H+

The 3 substrates of this enzyme are formaldehyde, NAD+, and H2O, whereas its 3 products are formate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is formaldehyde:NAD+ oxidoreductase. Other names in common use include NAD+-linked formaldehyde dehydrogenase, s-nitrosoglutathione reductase (GSNO reductase) and NAD+-dependent formaldehyde dehydrogenase. This enzyme participates in methane metabolism.

and 23 Related for: Formaldehyde dehydrogenase information

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Formaldehyde dehydrogenase

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In enzymology, a formaldehyde dehydrogenase (EC 1.2.1.46) is an enzyme that catalyzes the chemical reaction formaldehyde + NAD+ + H2O ⇌ {\displaystyle...

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Alcohol dehydrogenase

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organisms showed that a glutathione-dependent formaldehyde dehydrogenase, identical to a class III alcohol dehydrogenase (ADH-3/ADH5), is presumed to be the ancestral...

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Formaldehyde

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convert methanol into formaldehyde and energy via methanol dehydrogenase: CH3OH → CH2O + 2e− + 2H+ Other routes to formaldehyde include oxidative demethylations...

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ADH5

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Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene. This gene encodes glutathione-dependent formaldehyde dehydrogenase or...

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Methylotroph

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reducing power. Methanol is then oxidized to formaldehyde through the action of methanol dehydrogenase (MDH) in bacteria, or a non-specific alcohol oxidase...

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Fomepizole

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first metabolized to formaldehyde by alcohol dehydrogenase. Formaldehyde then undergoes further oxidation, via formaldehyde dehydrogenase, to become formic...

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Methanol toxicity

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formaldehyde in a process initiated by the enzyme alcohol dehydrogenase in the liver. Methanol is converted to formaldehyde via alcohol dehydrogenase...

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Methanol

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formaldehyde in a process initiated by the enzyme alcohol dehydrogenase in the liver. Methanol is converted to formaldehyde via alcohol dehydrogenase...

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Methanol dehydrogenase

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In enzymology, a methanol dehydrogenase (MDH) is an enzyme that catalyzes the chemical reaction: CH3OH ⇌ {\displaystyle \rightleftharpoons } CH2O + 2...

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Dimethylglycine dehydrogenase

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In enzymology, a dimethylglycine dehydrogenase (EC 1.5.8.4) is an enzyme that catalyzes the chemical reaction N,N-dimethylglycine + acceptor + H2O ⇌ {\displaystyle...

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Methylglutamate dehydrogenase

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In enzymology, a methylglutamate dehydrogenase (EC 1.5.99.5) is an enzyme that catalyzes the chemical reaction N-methyl-L-glutamate + acceptor + H2O ⇌...

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Mycothiol

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biosynthesis and mycothiol-dependent enzymes such as mycothiol-dependent formaldehyde dehydrogenase and mycothione reductase have been proposed to be good drug targets...

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Dimethylamine dehydrogenase

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In enzymology, a dimethylamine dehydrogenase (EC 1.5.8.1) is an enzyme that catalyzes the chemical reaction dimethylamine + H2O + electron-transferring...

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Trimethylamine dehydrogenase

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In enzymology, a trimethylamine dehydrogenase (EC 1.5.8.2) is an enzyme that catalyzes the chemical reaction trimethylamine + H2O + electron-transferring...

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Ogataea polymorpha

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be observed for enzymes called MOX (methanol oxidase), FMDH (formate dehydrogenase), and DHAS (dihydroxyacetone synthase). Their presence is regulated...

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Sarcosine dehydrogenase

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catalyzed by sarcosine dehydrogenase is: sarcosine + acceptor + H2O ⇌ {\displaystyle \rightleftharpoons } glycine + formaldehyde + reduced acceptor There...

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Aldehyde

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single bond to a third substituent, which is carbon or, in the case of formaldehyde, hydrogen. The central carbon is often described as being sp2-hybridized...

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Acetaldehyde

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in quantities sufficient to cause problems. Alcohol dehydrogenase Disulfiram-like drug Formaldehyde Paraldehyde Wine fault SciFinderScholar (accessed 4...

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Hair of the dog

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via formaldehyde coincides with the rate of appearance of hangover symptoms. As both ethanol and methanol are metabolized by alcohol dehydrogenase – and...

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Ethanol

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competitive inhibitor against methanol and ethylene glycol for alcohol dehydrogenase. Though it has more side effects, ethanol is less expensive and more...

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Isopropyl alcohol

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isopropyl alcohol provides a comparatively non-toxic alternative to formaldehyde and other synthetic preservatives. Isopropyl alcohol solutions of 70–99%...

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Toxication

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but it can be converted to formaldehyde by alcohol dehydrogenase and then converted to formic acid by aldehyde dehydrogenase, which are significantly more...

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Hangover

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some, such as methanol, are metabolized to the notably toxic substances formaldehyde and formic acid. After being ingested, the ethanol in alcoholic beverages...

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