Electron micrograph of shadowed filamentous bacteriophage (inovirus)
Virus classification
(unranked):
Virus
Realm:
Monodnaviria
Kingdom:
Loebvirae
Phylum:
Hofneiviricota
Class:
Faserviricetes
Order:
Tubulavirales
Family:
Inoviridae
Genera
See text
Filamentous bacteriophages are a family of viruses (Inoviridae) that infect bacteria, or bacteriophages. They are named for their filamentous shape, a worm-like chain (long, thin, and flexible, reminiscent of a length of cooked spaghetti), about 6 nm in diameter and about 1000-2000 nm long.[1][2][3][4][5] This distinctive shape reflects their method of replication: the coat of the virion comprises five types of viral protein, which are located in the inner membrane of the host bacterium during phage assembly, and these proteins are added to the nascent virion's DNA as it is extruded through the membrane. The simplicity of filamentous phages makes them an appealing model organism for research in molecular biology, and they have also shown promise as tools in nanotechnology and immunology.
^Hay ID, Lithgow T (June 2019). "Filamentous phages: masters of a microbial sharing economy". EMBO Reports. 20 (6): e47427. doi:10.15252/embr.201847427. PMC 6549030. PMID 30952693.
^Straus SK, Bo HE (2018). "Filamentous Bacteriophage Proteins and Assembly". In Bhella JR, Harris D (eds.). Virus Protein and Nucleoprotein Complexes. Subcellular Biochemistry. Vol. 88. Springer Singapore. pp. 261–279. doi:10.1007/978-981-10-8456-0_12. ISBN 978-981-10-8455-3. PMID 29900501.
^Mai-Prochnow A, Hui JG, Kjelleberg S, Rakonjac J, McDougald D, Rice SA (July 2015). "Big things in small packages: the genetics of filamentous phage and effects on fitness of their host". FEMS Microbiology Reviews. 39 (4): 465–87. doi:10.1093/femsre/fuu007. hdl:10453/65260. PMID 25670735.
^Rakonjac J, Russel M, Khanum S, Brooke SJ, Rajič M (2017). "Filamentous Phage: Structure and Biology". In Lim TS (ed.). Recombinant Antibodies for Infectious Diseases. Advances in Experimental Medicine and Biology. Vol. 1053. Springer International Publishing. pp. 1–20. doi:10.1007/978-3-319-72077-7_1. ISBN 978-3-319-72076-0. PMID 29549632.
^Roux S, Krupovic M, Daly RA, Borges AL, Nayfach S, Schulz F, et al. (November 2019). "Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth's biomes". Nature Microbiology. 4 (11): 1895–1906. doi:10.1038/s41564-019-0510-x. PMC 6813254. PMID 31332386.
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A bacteriophage (/bækˈtɪərioʊfeɪdʒ/), also known informally as a phage (/ˈfeɪdʒ/), is a virus that infects and replicates within bacteria and archaea...
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PMID 5807970. Lopez, J; Webster, RE (May 1983). "Morphogenesis of filamentousbacteriophage f1: orientation of extrusion and production of polyphage". Virology...
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alpha-helical protein that forms a viral envelope of filamentousbacteriophages. These bacteriophages are flexible rods, about one to two micrometres long...
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conditions. The end result is the peptides produced by bacteriophage are specific. The resulting filamentous phages can infect gram-negative bacteria once again...
RDCs were between -40 and +20 Hz. Rod-shaped viruses, including filamentousbacteriophage (large anisotropic magnetic susceptibility). DNA nanotubes (compatible...
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are bacteriophages which infect and destroy marine bacteria and control the growth of phytoplankton at the base of the marine food web. Bacteriophages are...
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proteins are made up of elongated or fibrous polypeptide chains which form filamentous and sheet-like structures. These kind of protein can be distinguished...
Prochloron, the N2-fixing filamentous cyanobacteria Nodularia spumigena, Lyngbya aestuarii and Lyngbya majuscula, as well as bacteriophages infecting marine cyanobaceria...
consisting of nine articles. Rakonjac, J., Das, B. Derda, R. 2017. FilamentousBacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology. ISBN 9782889450954...
University of Cambridge, where he worked with Richard Perham on filamentousbacteriophages; and his MD from University of California Los Angeles in 1989...
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