Ff phages (for F specific filamentous phages) is a group of almost identical filamentous phage (genus Inovirus) including phages f1, fd, M13 and ZJ/2, which infect bacteria bearing the F fertility factor.[1][2][3][4][5][6][7] The virion (virus particle) is a flexible filament measuring about 6 by 900 nm, comprising a cylindrical protein tube protecting a single-stranded circular DNA molecule at its core. The phage codes for only 11 gene products, and is one of the simplest viruses known. It has been widely used to study fundamental aspects of molecular biology. George Smith and Greg Winter used f1 and fd for their work on phage display for which they were awarded a share of the 2018 Nobel Prize in Chemistry.[8] Early experiments on Ff phages used M13 to identify gene functions,[9][10] and M13 was also developed as a cloning vehicle,[11] so the name M13 is sometimes used as an informal synonym for the whole group of Ff phages.
^Rasched I, Oberer E (December 1986). "Ff coliphages: structural and functional relationships". Microbiological Reviews. 50 (4): 401–27. doi:10.1128/MR.50.4.401-427.1986. PMC 373080. PMID 3540571.
^Mai-Prochnow A, Hui JG, Kjelleberg S, Rakonjac J, McDougald D, Rice SA (July 2015). "'Big things in small packages: the genetics of filamentous phage and effects on fitness of their host'". FEMS Microbiology Reviews. 39 (4): 465–87. doi:10.1093/femsre/fuu007. hdl:10453/65260. PMID 25670735.
^Rakonjac J, Bas B, Derda R, eds. (2017). Filamentous Bacteriophage in Bio/Nano/Technology, Bacterial Pathogenesis and Ecology. Frontiers Research Topics. Frontiers Media SA. doi:10.3389/978-2-88945-095-4. ISBN 978-2-88945-095-4.
^Morag O, Abramov G, Goldbourt A (December 2011). "Similarities and differences within members of the Ff family of filamentous bacteriophage viruses". The Journal of Physical Chemistry B. 115 (51): 15370–9. doi:10.1021/jp2079742. PMID 22085310.
^Hay ID, Lithgow T (June 2019). "Filamentous phages: masters of a microbial sharing economy". EMBO Reports. 20 (6). doi:10.15252/embr.201847427. PMC 6549030. PMID 30952693.
^Rakonjac J, Bennett NJ, Spagnuolo J, Gagic D, Russel M (2011). "Filamentous bacteriophage: biology, phage display and nanotechnology applications". Current Issues in Molecular Biology. 13 (2): 51–76. PMID 21502666.
^Rakonjac J, Russel M, Khanum S, Brooke SJ, Rajič M (2017). "Filamentous Phage: Structure and Biology". In Lim TS (ed.). Recombinant Antibodies for Infectious Diseases. Advances in Experimental Medicine and Biology. Vol. 1053. Cham: Springer International Publishing. pp. 1–20. doi:10.1007/978-3-319-72077-7_1. ISBN 978-3-319-72076-0. PMID 29549632.
^"The Nobel Prize in Chemistry 2018". NobelPrize.org. Retrieved 2021-04-10.
^Pratt D, Tzagoloff H, Erdahl WS (November 1966). "Conditional lethal mutants of the small filamentous coliphage M13. I. Isolation, complementation, cell killing, time of cistron action". Virology. 30 (3): 397–410. doi:10.1016/0042-6822(66)90118-8. PMID 5921643.
^Pratt D, Tzagoloff H, Beaudoin J (September 1969). "Conditional lethal mutants of the small filamentous coliphage M13. II. Two genes for coat proteins". Virology. 39 (1): 42–53. doi:10.1016/0042-6822(69)90346-8. PMID 5807970.
^Messing J (April 1991). "Cloning in M13 phage or how to use biology at its best". Gene. 100: 3–12. doi:10.1016/0378-1119(91)90344-b. PMID 2055478.
Ffphages (for F specific filamentous phages) is a group of almost identical filamentous phage (genus Inovirus) including phages f1, fd, M13 and ZJ/2,...
not matter whether the antigen remains bound to the phage. The issue of using Ffphages for phage display is that they require the protein of interest...
M13 is one of the Ffphages (fd and f1 are others), a member of the family filamentous bacteriophage (inovirus). Ffphages are composed of circular single-stranded...
Phages fd, f1, M13 and other related phages are Ffphages, for F specific (they infect Escherichia coli carrying the F-episome) filamentous phages, using...
undergoing a lysogenic cycle the phage genome exists as a plasmid in the bacterium unlike other phages (e.g. the lambda phage) that integrate into the host...
structural comparisons of native and mutant class I filamentous bacteriophages Ff (fd, f1, M13), If1 and IKe" (PDF). J. Mol. Biol. 235 (1): 260–86. doi:10...
for proteins needed for phage packaging and secretion (Psh, Cep, OrfU, Ace and Zot), which are very similar to the genes of Ff filamentous coliphages....
Earth, the Fantastic Four and the mind of Mister Fantastic. Starring the FF, She–Hulk, Jack of Hearts, the Unseen, the Silver Surfer and everyone in the...
Ultimate FF, no. 4 (Sept. 2014). New York: Marvel Comics. Johnston, Rich (July 30, 2014). "Joshua Hale Fialkov's Final Scene From Ultimate FF Is A Cut...
are: LB – 'late blight' V – verticillium wilt F – fusarium wilt strain I FF – fusarium wilt strain I and II N – nematodes T – tobacco mosaic virus, and...
gov. Archived from the original on 2015-07-04. Retrieved 2015-07-19. Ferri FF (2010). "Chapter T". Ferri's differential diagnosis : a practical guide to...
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Tocchini (p), Paul Mounts (col), Clayton Cowles (let), Tom Brevoort (ed). FF, no. 6 (13 July 2011). United States: Marvel Comics. Stan Lee (w), Jack Kirby (p)...
Lives From Ancient Times to the Mid-20th Century. Taylor & Francis. pp. 2830 ff. ISBN 978-1-135-96342-2. Robin, Diana Maury; Larsen, Anne R.; Levin, Carole...
of an organism". Biokhimiya. 64 (12): 1418–1426. PMID 10648966. Severin, FF; Skulachev, VP (2011). "Programmed Cell Death as a Target to Interrupt the...
defender, FF Lugano 1976 Ásthildur Helgadóttir – Icelandic soccer player, Iceland women's national football team (1993–2007), Breiðablik, KR, Malmö FF Dam Tony...
original on 26 June 2015. Retrieved 26 July 2015. Han HJ, Wen HL, Zhou CM, Chen FF, Luo LM, Liu JW, Yu XJ (2015). "Bats as reservoirs of severe emerging infectious...
using aniline dyes (1886), some studies on anthrax in collaboration with F.F. Wesbrook, immunity and the role of "alexins". He extracted an albumose fraction...
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