Non-soluble proteins with elongated or sheet-like structures
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Tropocollagen triple helix
In molecular biology, fibrous proteins or scleroproteins are one of the three main classifications of protein structure (alongside globular and membrane proteins).[1] Fibrous proteins are made up of elongated or fibrous polypeptide chains which form filamentous and sheet-like structures. These kind of protein can be distinguished from globular protein by its low solubility in water. Such proteins serve protective and structural roles by forming connective tissue, tendons, bone matrices, and muscle fiber.
Fibrous proteins consist of many superfamilies including keratin, collagen, elastin, and fibrin. Collagen is the most abundant of these proteins which exists in vertebrate connective tissue including tendon, cartilage, and bone.[2]
^Andreeva, A (2014). "SCOP2 prototype: a new approach to protein structure mining". Nucleic Acids Res. 42 (Database issue): D310-4. doi:10.1093/nar/gkt1242. PMC 3964979. PMID 24293656.
^Shoulders, MD; Raines, RT (2009). "Collagen structure and stability". Annual Review of Biochemistry. 78: 929–58. doi:10.1146/annurev.biochem.77.032207.120833. PMC 2846778. PMID 19344236.
fibrousproteins or scleroproteins are one of the three main classifications of protein structure (alongside globular and membrane proteins). Fibrous...
globular proteins or spheroproteins are spherical ("globe-like") proteins and are one of the common protein types (the others being fibrous, disordered...
: 368–75 Proteins can be informally divided into three main classes, which correlate with typical tertiary structures: globular proteins, fibrousproteins, and...
Keratin (/ˈkɛrətɪn/) is one of a family of structural fibrousproteins also known as scleroproteins. Alpha-keratin (α-keratin) is a type of keratin found...
Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin...
Pea protein is a food product and protein supplement derived and extracted from yellow and green split peas, Pisum sativum. It can be used as a dietary...
observable through kinetic experiments. Fibrousproteins, such as proteins involved in Alzheimer's disease and prion proteins fulfil the requirements for UV LD...
cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrousproteins fill the interstitial space and act as a compression buffer against...
spines. The spines are modified hairs and are made of keratin, the same fibrousprotein that makes up fur, claws, nails, and horn sheaths in animals. Superficially...
cells. The predominant cell keratinocyte, which produces keratin, a fibrousprotein that aids in skin protection, is responsible for the formation of the...
Proc. Am. Philos. Soc., 85, 1–12. Huggins M. (1943) "The structure of fibrousproteins", Chem. Rev., 32, 195–218. Olby, Robert (1970). "Astbury, William Thomas"...
alternating dark and light bands. Sarcomeres are composed of long, fibrousproteins as filaments that slide past each other when a muscle contracts or...
of ground substance to fibrous tissue. Loose connective tissue has much more ground substance and a relative lack of fibrous tissue, while the reverse...
with the lipid bilayer. Membrane proteins, like soluble globular proteins, fibrousproteins, and disordered proteins, are common. It is estimated that...
has a mass of roughly 90 kilodaltons. A 90 kDa protein is considered fairly large for a non-fibrousprotein. Hsp90 is found in bacteria and all branches...
is extruded, causing a change in the structure of the soy protein which results in a fibrous, spongy matrix, similar in texture to meat. In its dehydrated...
functions such as detoxification of the organism, and the synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it is located...
also known as fibrousproteins or protein filaments, consist largely of biologically relevant and biologically very important proteins, in which mutations...
protein often allows functional prediction as well. For instance, collagen is folded into a long-extended fiber-like chain and it makes it a fibrous protein...
designed elastin-like fibrous peptides based on rules on sequence composition. Richardson and coworkers designed a 79-residue protein with no sequence homology...
healing process. Chemically speaking, this is calcium carbonate and a fibrousprotein called conchiolin. As the nacre builds up in layers of minute aragonite...
matrix of the supporting branch. These branches are composed of a fibrousprotein called gorgonin or of a calcified material. The polyps of stony corals...
strength but has strong adhesive properties due to its insoluble and fibrousprotein composition. In recent studies, silk fibroin has been found to possess...
Fibrous dysplasia is a very rare nonhereditary genetic disorder where normal bone and marrow is replaced with fibrous tissue, resulting in formation of...
enzyme that catalyses the hydrolysis of starch into sugars Amyloid, fibrousprotein aggregates, originally named in the mistaken belief that they contained...
bone in the mandible which the body replaces with excessive amounts of fibrous tissue. In most cases, the condition fades as the child grows, but in rare...
are one of the common types of protein along with soluble globular proteins, fibrousproteins, and disordered proteins. They are targets of over 50% of...
needed] The extracellular matrix of the vocal cord LP is composed of fibrousproteins such as collagen and elastin, and interstitial molecules such as HA...
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