A fatty streak is the first grossly visible (visible to the naked eye) lesion in the development of atherosclerosis. It appears as an irregular yellow-white discoloration on the luminal surface of an artery. It consists of aggregates of foam cells, which are lipoprotein-loaded macrophages,[1] located in the intima, the innermost layer of the artery, beneath the endothelial cells that layer the lumina through which blood flows. Fatty streaks may also include T cells, aggregated platelets, and smooth muscle cells. Although fatty streaks can develop into atheromas (atheromatous plaques), not all are destined to become advanced lesions.[2]
^Guyton, Arthur C.; Hall, John E. (2006). Textbook of Medical Physiology (11th ed.). Philadelphia: Elsevier Saunders. p. 849. ISBN 978-0-7216-0240-0.
^Kumar, Vinay; Abbas, Abul K.; Aster, Jon C.; Turner, Jerrold R.; Perkins, James A.; Robbins, Stanley L.; Cotran, Ramzi S., eds. (2021). Robbins & Cotran Pathologic Basis of Disease (10th ed.). Philadelphia, PA: Elsevier. p. 499. ISBN 978-0-323-53113-9.
A fattystreak is the first grossly visible (visible to the naked eye) lesion in the development of atherosclerosis. It appears as an irregular yellow-white...
gelatinous lesions have been observed in the coronary arteries of children. Fattystreaks have been observed in the coronary arteries of juveniles. While coronary...
Trans fat, also called trans-unsaturated fatty acids, or trans fatty acids, is a type of unsaturated fat that occurs in foods. Trace concentrations of...
early stages, based on gross appearance, have traditionally been termed fattystreaks by pathologists, they are not composed of fat cells but of accumulations...
which is a specific form of arteriosclerosis caused by the buildup of fatty plaques, cholesterol, and some other substances in and on the artery walls...
isomer ratio is about 2:1. Numerous studies have concluded that these trans fatty acids have negative health effects. As a result, many countries have enacted...
membrane, alongside the nonpolar fatty-acid chain of the other lipids. Through the interaction with the phospholipid fatty-acid chains, cholesterol increases...
approximately a tripling of risk with each decade of life. Coronary fattystreaks can begin to form in adolescence. It is estimated that 82 percent of...
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