Four and a half LIM domains protein 2 also known as FHL-2 is a protein that in humans is encoded by the FHL2 gene.[5] LIM proteins contain a highly conserved double zinc finger motif called the LIM domain.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000115641 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000008136 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Morgan MJ, Madgwick AJ (October 1996). "Slim defines a novel family of LIM-proteins expressed in skeletal muscle". Biochem. Biophys. Res. Commun. 225 (2): 632–8. doi:10.1006/bbrc.1996.1222. PMID 8753811.
^"Entrez Gene: FHL2 four and a half LIM domains 2".
protein 2 also known as FHL-2 is a protein that in humans is encoded by the FHL2 gene. LIM proteins contain a highly conserved double zinc finger motif called...
lymphoproliferative diseases and termed EBV+ HLH. Five genetic subtypes (FHL1, FHL2, FHL3, FHL4, and FHL5) are described, with an estimated overall prevalence...
associated with egg-spot patterning and color arrangement. These are fhl2-a and fhl2-b, which are paralogs. These genes aid in pattern formation and cell-fate...
gravis. Titin has been shown to interact with: ANK1, ANKRD1, ANKRD23 CAPN3, FHL2, OBSCN, TCAP, and TRIM63. The name titin is derived from the Greek Titan...
Zhong H, Lu Q, Huang C, Ye Q (October 2003). "BRCA1 interacts with FHL2 and enhances FHL2 transactivation function". FEBS Lett. 553 (1–2): 183–9. doi:10...
autoimmune disease spondyloarthritis. CD18 has been shown to interact with: FHL2, GNB2L1, ICAM-1, and PSCD1. leukocyte adhesion deficiency integrin GRCh38:...
Cardiac-enriched FHL2-interacting protein (CEFIP) is a protein encoded by the gene C10orf71 on chromosome 10 open reading frame 71. It is primarily understood...
Pscherer A, Breyer T, Holubarsch C, Buettner R, Schüle R (February 2000). "FHL2, a novel tissue-specific coactivator of the androgen receptor". The EMBO...
variants has not been determined. ZNF638 has been shown to interact with FHL2. GRCh38: Ensembl release 89: ENSG00000075292 – Ensembl, May 2017 GRCm38:...
into the cytoplasm of the cell. EpICD forms a complex with the proteins FHL2, β-catenin, and Lef inside the nucleus. This complex then binds to DNA and...
proteins have been reported. TRAF6 has been shown to interact with: ASK1, CD40, FHL2, HSPB2, IKBKG, IRAK1, IRAK2, TAB1, MAP3K7IP2, MAP3K7 PPP4C, RANK, SDCBP,...
regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2". Molecular and Cellular Biology. 24 (22): 9835–47. doi:10.1128/MCB.24.22...
Carlile G, Licht JD, Schäfer BW (October 2002). "The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger...
inflammation or emphysema. Integrin beta 6 has been shown to interact with FHL2. GRCh38: Ensembl release 89: ENSG00000115221 – Ensembl, May 2017 GRCm38:...
Wixler V, Geerts D, Laplantine E, et al. (2000). "The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains...
cytoplasm localization and is ubiquitously expressed Fanconi anemia disease FHL2 Four and a half LIM domains protein 2 Two hybrid prey Localized in the cytoplasm...
structures, bound to the four and one half LIM domain proteins, FHL1 and FHL2. It has been demonstrated that alpha-7 integrin can be mono-ADP-ribosylated...
M508931200. PMID 16316995. Sun J, Yan G, Ren A, You B, Liao JK (September 2006). "FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine...
element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3". Small GTPases. 10 (5): 361–366. doi:10.1080/21541248.2017.1327838...
dilated cardiomyopathy, two of which result in altered binding with TLN1 and FHL2. Mutations in ANKRD1 have also been associated with hypertrophic cardiomyopathy...
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