Global Information Lookup Global Information

Equilibrative nucleoside transporter 1 information


SLC29A1
Identifiers
AliasesSLC29A1, ENT1, Equilibrative nucleoside transporter 1, solute carrier family 29 member 1 (Augustine blood group)
External IDsOMIM: 602193; MGI: 1927073; HomoloGene: 37985; GeneCards: SLC29A1; OMA:SLC29A1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)Chr 6: 44.22 – 44.23 MbChr 17: 45.59 – 45.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Equilibrative nucleoside transporter 1 (ENT1) is a protein that in humans is encoded by the SLC29A1 gene.[5][6] Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.[7] Expressed on red blood cell surfaces, these variants make up the Augustine blood group system.[8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000112759 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023942 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Griffiths M, Beaumont N, Yao SY, Sundaram M, Boumah CE, Davies A, et al. (January 1997). "Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs". Nature Medicine. 3 (1): 89–93. doi:10.1038/nm0197-89. PMID 8986748. S2CID 10182379.
  6. ^ Coe IR, Griffiths M, Young JD, Baldwin SA, Cass CE (October 1997). "Assignment of the human equilibrative nucleoside transporter (hENT1) to 6p21.1-p21.2". Genomics. 45 (2): 459–60. doi:10.1006/geno.1997.4928. PMID 9344680.
  7. ^ Cite error: The named reference entrez was invoked but never defined (see the help page).
  8. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).

and 28 Related for: Equilibrative nucleoside transporter 1 information

Request time (Page generated in 0.9044 seconds.)

Equilibrative nucleoside transporter 1

Last Update:

Equilibrative nucleoside transporter 1 (ENT1) is a protein that in humans is encoded by the SLC29A1 gene. Multiple alternatively spliced variants, encoding...

Word Count : 1274

Equilibrative nucleoside transporter 2

Last Update:

Equilibrative nucleoside transporter 2 (ENT2) is a protein that in humans is encoded by the SLC29A2 gene. Solute carrier family Equilibrative nucleoside...

Word Count : 851

Equilibrative nucleoside transporter family

Last Update:

Members of the Equilibrative Nucleoside Transporter (ENT) Family (TC# 2.A.57) are transport proteins that are specific to nucleosides and nucleobases,...

Word Count : 635

Nucleoside transporter

Last Update:

known types of nucleoside transporters, concentrative nucleoside transporters (CNTs; SLC28) and equilibrative nucleoside transporters (ENTs; SLC29), as...

Word Count : 222

Neurotransmitter transporter

Last Update:

monoamine transporter 2 (VMAT2) Adenosine transporters, including: Equilibrative nucleoside transporter 1 (ENT1) Equilibrative nucleoside transporter 2 (ENT2)...

Word Count : 988

Plasma membrane monoamine transporter

Last Update:

the SLC29A4 gene. It is known alternatively as the human equilibrative nucleoside transporter-4 (hENT4). It was discovered in 2004 and has been identified...

Word Count : 1447

Nucleoside

Last Update:

Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group. A nucleoside consists simply of a nucleobase (also termed...

Word Count : 851

Concentrative nucleoside transporter 2

Last Update:

Concentrative nucleoside transporter 2 (CNT2) is a protein that in humans is encoded by the SLC28A2 gene. Concentrative nucleoside transporters Nucleoside transporters...

Word Count : 907

Concentrative nucleoside transporter 1

Last Update:

Concentrative nucleoside transporter 1 (CNT1) is a protein that in humans is encoded by the SLC28A1 gene. Concentrative nucleoside transporters Nucleoside transporters...

Word Count : 877

Trifluridine

Last Update:

concentrative nucleoside transporter 1 (CNT1) and equilibrative nucleoside transporters 1 (ENT1) and 2 (ENT2). Drugs that interact with these transporters could...

Word Count : 739

Augustine blood group system

Last Update:

Augustine antigens is equilibrative nucleoside transporter 1, a transmembrane glycoprotein that mediates cellular uptake of nucleosides. This protein is abundant...

Word Count : 446

Uniporter

Last Update:

cancer metabolism. The nucleoside transporters, or equilibrative nucleoside transporters, are uniporters that transport nucleosides, nucleobases, and therapeutic...

Word Count : 3212

Nucleotide

Last Update:

fundamental, cellular level. They provide chemical energy—in the form of the nucleoside triphosphates, adenosine triphosphate (ATP), guanosine triphosphate (GTP)...

Word Count : 3299

Solute carrier family

Last Update:

Yao SY, King AE, Cass CE, Young JD (February 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Archiv. 447 (5): 735–743. doi:10...

Word Count : 3408

HEK 293 cells

Last Update:

293 cell line. This mutant strain does not express of the equilibrative nucleoside transporter ENT1. The gene was knocked out using CRISPR-CAS9 and the...

Word Count : 3065

H syndrome

Last Update:

by mutations in the SLC29A3 gene which encode the human equilibrative nucleoside transporter (hENT3) protein. It is also known as Faisalabad histiocytosis...

Word Count : 370

Adenosine reuptake inhibitor

Last Update:

for the purine nucleoside and neurotransmitter adenosine by blocking the action of one or more of the equilibrative nucleoside transporters (ENTs). This...

Word Count : 1581

Pyrimidine

Last Update:

showed how pyrimidine nucleosides can be synthesized from small molecules and ribose, driven solely by wet-dry cycles. Purine nucleosides can be synthesized...

Word Count : 2105

Adenosine

Last Update:

cells and the vessel wall. Dipyridamole, an inhibitor of adenosine nucleoside transporter, allows adenosine to accumulate in the blood stream. This causes...

Word Count : 3346

Transporter Classification Database

Last Update:

(Mn2+-iron) Transporter (Nramp) Family 2.A.56 The Tripartite ATP-independent Periplasmic Transporter (TRAP-T) Family 2.A.57 The Equilibrative Nucleoside Transporter...

Word Count : 5159

Purine

Last Update:

purine bases are guanine (G) and adenine (A) which form corresponding nucleosides-deoxyribonucleosides (deoxyguanosine and deoxyadenosine) with deoxyribose...

Word Count : 2510

Inosine

Last Update:

Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring (also known as a ribofuranose) via a β-N9-glycosidic bond. It was...

Word Count : 1252

Uridine monophosphate

Last Update:

used as a monomer in RNA. It is an ester of phosphoric acid with the nucleoside uridine. UMP consists of the phosphate group, the pentose sugar ribose...

Word Count : 487

Cytosine

Last Update:

attached (an amine group at position 4 and a keto group at position 2). The nucleoside of cytosine is cytidine. In Watson–Crick base pairing, it forms three...

Word Count : 903

Dipyridamole

Last Update:

potentiate the effects of adenosine. This occurs by blocking the nucleoside transporter (ENT1) through which adenosine enters erythrocyte and endothelial...

Word Count : 1256

Purine metabolism

Last Update:

nuclease frees the nucleotide A nucleotidase creates guanosine Purine nucleoside phosphorylase converts guanosine to guanine Guanase converts guanine to...

Word Count : 1635

Guanosine triphosphate

Last Update:

Guanosine-5'-triphosphate (GTP) is a purine nucleoside triphosphate. It is one of the building blocks needed for the synthesis of RNA during the transcription...

Word Count : 607

Guanine

Last Update:

(uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is called guanosine. With the formula C5H5N5O, guanine is a derivative...

Word Count : 1523

PDF Search Engine © AllGlobal.net