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Epsin information


Epsins are a family of highly conserved membrane proteins that are important in creating membrane curvature. Epsins contribute to membrane deformations like endocytosis, and block vesicle formation during mitosis.[1]

Crystal Structure of the ENTH Domain of Rattus norvegicus Epsin1
  1. ^ Sen A, Madhivanan K, Mukherjee D, Aguilar RC (Apr 2012). "The epsin protein family: coordinators of endocytosis and signaling". Biomolecular Concepts. 3 (2): 117–126. doi:10.1515/bmc-2011-0060. PMC 3431554. PMID 22942912.

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Epsin

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Epsins are a family of highly conserved membrane proteins that are important in creating membrane curvature. Epsins contribute to membrane deformations...

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Clathrin

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AP180 and epsin. AP180 is used in synaptic vesicle formation. It recruits clathrin to membranes and also promotes its polymerization. Epsin also recruits...

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Espoon Palloseura

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kilpailullinen jalkapalloseura, Länsiväylä, 12 December 2020 Jussi Leppälahti kertoo EPSin edustuksen kulttuurin muutoksesta – ”Marraskuun ensimmäisissä treeneissä...

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ENTH domain

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The epsin N-terminal homology (ENTH) domain is a structural domain that is found in proteins involved in endocytosis and cytoskeletal machinery. This...

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Gary Struhl

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with Epsin can be seen in a two decade span of several papers. His first major paper regarding Epsin was written in 2004, titled “Drosophila Epsin mediates...

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CLINT1

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A, Kelly K, Morgan J, Punukollu B, Curtis D, Gurling H (May 2005). "The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin...

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Inositol

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including: Insulin signal transduction Cytoskeleton assembly Nerve guidance (epsin) Intracellular calcium (Ca2+) concentration control Cell membrane potential...

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EPN1

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Epsin-1 is a protein that in humans is encoded by the EPN1 gene. EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha...

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Membrane curvature

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protein epsin is an example. Epsin has an ENTH (epsin N-terminal homology) domain which inserts its amphipathic alpha helix into the membrane. Epsin has high...

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EPN

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organisation Entomopathogenic nematode, thread worm that kills insects Epsin, a membrane protein Esplanade MRT station, Singapore (MRT station abbreviation)...

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EPN2

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Epsin-2 is a protein that in humans is encoded by the EPN2 gene. This gene encodes a protein which interacts with clathrin and adaptor-related protein...

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BAR domain

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amphipathic helix preceding the BAR domain. This helix inserts (like in the epsin ENTH domain) into the membrane and induces curvature, which is stabilised...

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AP2A2

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VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (Aug 1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis"...

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REPS2

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Nakashima S, Hinoi T, Okawa K, Iwamatsu A, Kikuchi A (October 1999). "Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis"...

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Amphiphysin

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interact with DNM1, Phospholipase D1, CDK5R1, PLD2, CABIN1 and SH3GL2. AP180 Epsin GRCh38: Ensembl release 89: ENSG00000078053 – Ensembl, May 2017 GRCm38:...

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EPS15

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Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (August 1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis"...

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Ap180

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endocytosis. More information is found on endocytosis.org. Amphiphysin Epsin Bao H, Daniels RW, MacLeod GT, Charlton MP, Atwood HL, Zhang B (2005). "AP180...

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AP2 adaptor complex

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for the development of familial Alzheimer's Disease. Amphiphysin AP180 Epsin Exomer Muniscins Pearse BM, Smith CJ, Owen DJ (April 2000). "Clathrin coat...

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RALBP1

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an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis". J. Biol. Chem. 278 (33):...

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Cyclin B1

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an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis". J. Biol. Chem. 278 (33):...

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ANTH domain

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membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains". J. Biol. Chem. 278 (31): 28993–9. doi:10...

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Vesicular transport adaptor protein

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this article. PTBs are protein domains that include NUMB, DAB1 and DAB2. Epsin and AP180 in the ANTH domain are other adaptor proteins that have been reviewed...

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Alpha Arrestin

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Andy; Aguilar, R. Claudio (2020-01-01). "The Na+ pump Ena1 is a yeast Epsin-specific cargo requiring its ubiquitination/phosphorylation sites for internalization"...

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EPS15L1

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Slepnev VI, Capua MR, Takei K, Butler MH, Di Fiore PP, De Camilli P (1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis"...

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