Clathrin assembly lymphoid myeloid leukemia (CALM) protein
Identifiers
Symbol
ANTH
Pfam
PF07651
InterPro
IPR011417
OPM superfamily
38
OPM protein
1hfa
CDD
cd03564
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
The ANTH domain is a membrane binding domain that shows weak specificity for PtdIns(4,5)P2. It was found in AP180 (homologous to CALM[1]) endocytotic accessory protein that has been implicated in the formation of clathrin-coated pits. The domain is involved in phosphatidylinositol 4,5-bisphosphate binding and is a universal adaptor for nucleation of clathrin coats.[2][3]
Its structure is a solenoid of 9 helices. The PtdIns(4,5)P2 binding residues are spread over several helices at the tip of the structure. The PtdIns(4,5)P2 binding sequence is Kx9Kx(K/R)(H/Y).
An ANTH domain is also found in HIP1 and HIP1R, and the PtdIns(4,5)P2 binding sequence is conserved.
^"Clathrin and its interactions with AP180". Archived from the original on 2007-03-11.
^de Camilli P, McMahon HT, Peter BJ, Stahelin RV, Cho W, Long F, Murray D (2003). "Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains". J. Biol. Chem. 278 (31): 28993–9. doi:10.1074/jbc.M302865200. PMID 12740367.
^Payne GS, Duncan MC (2003). "ENTH/ANTH domains expand to the Golgi". Trends Cell Biol. 13 (5): 211–5. doi:10.1016/S0962-8924(03)00076-X. PMID 12742163.
The ANTHdomain is a membrane binding domain that shows weak specificity for PtdIns(4,5)P2. It was found in AP180 (homologous to CALM) endocytotic accessory...
domain and certain PDZ domains. They bind PtdIns(4,5)P2. Discoidin domains of blood coagulation factors ENTH, VHS and ANTHdomains Structural domains...
Peter (20 October 2005). "Sequence analysis of Arabidopsis thaliana E/ANTH-domain-containing proteins: membrane tethers of the clathrin-dependent vesicle...
It is capable of simultaneously binding both membrane lipids (via an ANTHdomain) and clathrin and is therefore thought to recruit clathrin to the membrane...
detail in this article. PTBs are protein domains that include NUMB, DAB1 and DAB2. Epsin and AP180 in the ANTHdomain are other adaptor proteins that have...
role for epsin N-terminal homology/AP180 N-terminal homology (ENTH/ANTH) domains in tubulin binding". J. Biol. Chem. 278 (31): 28823–30. doi:10.1074/jbc...
role for epsin N-terminal homology/AP180 N-terminal homology (ENTH/ANTH) domains in tubulin binding". The Journal of Biological Chemistry. 278 (31):...
article incorporates text in the public domain from page 174 of the 20th edition of Gray's Anatomy (1918) "ANTH 6 Forensic Anthropology Measuring Adult...
to be classed with the Alexandrian school of poets. Prooem 45; Anth. Pal. iv. 1. Anth. Pal. v. 161, 199; vi. 292; xi. 123, 414. Smith, p. 366. "Hedylus"...
135. Antist. Anth. Pal. 11. 40, Callim. 3. 14. Attribution: This article incorporates text from these sources, which are in the public domain. Edmonds, J...
nmap.online-domain-tools.com - An online Nmap scanner Techtarget.com - An article on idle scanning Seclists.org - Original bugtraq post ANTH Blog - Idle...
2007-11-04{{citation}}: CS1 maint: location missing publisher (link) Callimachus, Anth. Gr. ix. 336 Theocritus, Epigr. vii Karl Otfried Müller, Arch. der Kunst...
with the Life and Death of Cartesmunda, the Fair Nun of Winchester, by Anth. Brewer (1655) It was revived at the King's Theatre in 1680, and reprinted...
v. p. 673 Richard François Philippe Brunck, Anal. vol. ii. p. 41 Jacobs, Anth. Graec. vol. ii. p. 42, vol. xiii. p. 959 Ath. xi. p. 475, f Ath. xv. p....
the Panathenaic procession passed. Plut. 753 D and Them. 1; Athen. 13.576. Anth. Gr. 7.306. Plut. Amat. 9. "But you will say, since it may be a man's misfortune...
[failed verification]. A description of a basterna is given by a poet in the Anth. Lat. iii. 183. Others call it a kind of chariot, and say it was drawn by...
the past. (Correct as of January 13th, 2018 - MCW Vendetta) Adam Brooks Anth Cava Caveman Ugg Charli Evans Edward Dusk Emman The Kid Gore Jake Andrewartha...
Cambridge Scholars Publishing. ISBN 978-1-4438-4007-1. "History of Nubia". Anth.ucsb.edu. Archived from the original on 21 June 2010. Retrieved 12 June 2010...
Hiero II. According to an epigram of Dioscorides in the Greek Anthology (Anth. Pal. vii.707) he restored the satyric drama in its original form. A considerable...
that the resident magistrate and civil commissioner of Namaqualand, Louis Anthing, undertook in 1862 to investigate reports of massacres of San bands in...
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