transcription elongation from RNA polymerase II promoter
snRNA transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
22936
192657
Ensembl
ENSG00000118985
ENSMUSG00000001542
UniProt
O00472
Q3UKU1
RefSeq (mRNA)
NM_012081
NM_138953
RefSeq (protein)
NP_036213
NP_620403
Location (UCSC)
Chr 5: 95.89 – 95.96 Mb
Chr 13: 75.85 – 75.92 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Elongation factor for RNA polymerase II 2 is a protein that in humans is encoded by the ELL2 gene.
[5]
The encoded protein is a component of the superelongation complex (SEC) and drives immunoglobulin synthesis in plasma cells. Sequence variation in ELL2 has been associated with multiple myeloma and altered immunoglobulin levels.
^ abcGRCh38: Ensembl release 89: ENSG00000118985 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000001542 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^
"Entrez Gene: Elongation factor for RNA polymerase II 2". Retrieved 2018-08-24.
and 25 Related for: Elongation factor for RNA polymerase II 2 information
ElongationfactorforRNApolymeraseII2 is a protein that in humans is encoded by the ELL2 gene. The encoded protein is a component of the superelongation...
RNApolymeraseII (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA...
In molecular biology, RNApolymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNApolymerase (DdRP), is an enzyme that...
RNApolymerase 1 (also known as Pol I) is, in higher eukaryotes, the polymerase that only transcribes ribosomal RNA (but not 5S rRNA, which is synthesized...
any polymerase) involves three main stages: Initiation, requiring the construction of the RNApolymerase complex on the gene's promoter Elongation, the...
(negative elongationfactor) is a four-subunit protein complex (NELF-A, NELF-B, NELF-C/NELF-D, and NELF-E) that negatively impacts transcription by RNA polymerase...
contrast, RNApolymerases synthesize RNA from ribonucleotides from either RNA or DNA.[citation needed] When synthesizing new DNA, DNA polymerase can add...
RNApolymeraseII, a subset of general transcription factors, and regulatory proteins known as SRB proteins[clarification needed]. RNApolymeraseII (also...
Reverse transcription polymerase chain reaction (RT-PCR) is a laboratory technique combining reverse transcription of RNA into DNA (in this context called...
fourth-largest subunit of RNA polymeraseII, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated...
aminoacyl tRNA synthetases. During protein synthesis, tRNAs with attached amino acids are delivered to the ribosome by proteins called elongationfactors, which...
transcription factors are necessary for transcription to occur. In bacteria, transcription initiation requires an RNApolymerase and a single GTF: sigma factor. In...
Transcription factorII B (TFIIB) is a general transcription factor that is involved in the formation of the RNApolymeraseII preinitiation complex (PIC)...
initiation factor that enables specific binding of RNApolymerase (RNAP) to gene promoters. It is homologous to archaeal transcription factor B and to eukaryotic...
of the alpha subunit of the elongationfactor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform...
(elongating) DNA strand. The precise time required forelongation depends both on the DNA polymerase used and on the length of the DNA target region to...
regions of RNApolymeraseII (RNA pol II) binding and non-coding RNA transcription. The level of RNA pol II–enhancer interaction and RNA transcript formation...
modification by transcription factors is another key regulatory factorfor transcription by RNApolymerase. In general, factors that lead to histone acetylation...
DNA in the RNApolymeraseII active site for transcription. The minimal PIC includes RNApolymeraseII and six general transcription factors: TFIIA, TFIIB...
polymerase pausing can also occur which blocks elongation and leads to gene repression. One of the examples is repression of IME4 gene by its asRNA RME2...
and translation. The polymerase is an enzyme and can aid in initiation, elongation, capping, methylation, polyadenylation and RNA polymerization. After...
eukaryotes, messenger RNA precursors (pre-mRNA) are transcribed in the nucleus from DNA by the enzyme, RNApolymeraseII. The pre-mRNA must undergo post-transcriptional...