Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Dihydrobiopterin (BH2) is a pteridine compound produced in the synthesis of L-DOPA, dopamine, serotonin, norepinephrine and epinephrine. It is restored to the required cofactor tetrahydrobiopterin by dihydrobiopterin reductase.
Dihydrobiopterin (BH2) is a pteridine compound produced in the synthesis of L-DOPA, dopamine, serotonin, norepinephrine and epinephrine. It is restored...
classes of substituted pteridines that have diverse biological roles. Dihydrobiopterin Pyrazine Pyrimidine Tetrahydrobiopterin International Union of Pure...
that in humans is encoded by the SPR gene. Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase; EC 1.1.1.153) catalyzes the NADPH-dependent reduction...
(dihydropteridine reductase) reduced pteridine derivative (quinonoid dihydrobiopterin).[citation needed] Tetrahydrobiopterin is available as a tablet for...
Blakley RL (May 1990). "Dissociation constants for dihydrofolic acid and dihydrobiopterin and implications for mechanistic models for dihydrofolate reductase"...
deficiency of the enzyme dihydrobiopterin reductase (DHPR), whose activity is needed to replenish quinonoid-dihydrobiopterin back into its tetrahydrobiopterin...
regenerated by hydration of the carbinolamine product of PAH to quinonoid dihydrobiopterin (qBH2), which is then reduced to BH4. PAH is proposed to use the morpheein...
to high levels of prolactin. By contrast, in classical PKU (without dihydrobiopterin involvement), prolactin levels would be relatively normal.[citation...
BH4 is used as a source of reducing equivalents and is recycled by dihydrobiopterin reductase (EC 1.5.1.33), BH4 activates heme-bound O2 by donating a...
even though their levels of tetrahydrobiopterin were replenished. Dihydrobiopterin Tetrahydrobiopterin Dystonia Phenylketonuria Salvage pathway Smith...
donors such as S-adenosyl methionine (SAMe), recycles the inactive dihydrobiopterin (BH2) into tetrahydrobiopterin (BH4), the necessary cofactor in various...
using dihydrofolate reductase. In addition, BH2 is recycled to BH4 by dihydrobiopterin reductase. In the de novo pathway, GTP is converted to 7,8-dihydroneopterin...
molecular formula C9H13N5O3 (molar mass: 239.235 g/mol) may refer to: Dihydrobiopterin (BH2) S2242 This set index page lists chemical structure articles associated...
demonstrated as an enzyme involved in the salvage of tetrahydrobiopterin from dihydrobiopterin A central eight-stranded beta-pleated sheet makes up the main feature...
Under physiological conditions, 4a-BH4 is dehydrated to quinonoid-dihydrobiopterin (q-BH2) by the enzyme pterin-4a-carbinolamine dehydrase (PCD) and a...
tyrosine, tyrosine to L-DOPA, and tryptophan to 5-HTP, oxidizing BH4 to dihydrobiopterin (BH2) in the process. BH2 must then be converted back to BH4 by the...
(HVA), 5-hydroxyindolacetic acid (HIAA), and elevated levels of 7,8-dihydrobiopterin, a compound produced in the synthesis of neurotransmitters. Sepiapterin...
process 7,8-dihydroneopterin 3'-triphosphate biosynthetic process dihydrobiopterin metabolic process regulation of blood pressure response to tumor necrosis...
cellular amino acid metabolic process L-phenylalanine catabolic process dihydrobiopterin metabolic process response to lead ion response to aluminum ion tetrahydrobiopterin...
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