Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat depression.[5] It is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class and is taken by mouth.[5] It is recommended that the need for further treatment be occasionally reassessed.[5] It may be less effective than its parent compound venlafaxine,[6] although some studies have found comparable efficacy.[7]
Common side effects include dizziness, trouble sleeping, increased sweating, constipation, sleepiness, anxiety, and sexual problems.[5] Serious side effects may include suicide in those under the age of 25, serotonin syndrome, bleeding, mania, and high blood pressure.[5] A withdrawal syndrome may occur if the dose is decreased or the medication is completely stopped.[5] It is unclear if use during pregnancy or breastfeeding is safe.[8]
Desvenlafaxine was approved for medical use in the United States in 2008.[5] In Europe its application for use was denied in 2009,[6] but it is available in Spain and Germany.[citation needed] In 2021, it was the 178th most commonly prescribed medication in the United States, with more than 2million prescriptions.[9][10]
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 Oct 2023.
^Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
^"Mental health". Health Canada. 9 May 2018. Retrieved 13 April 2024.
^"Desvenlafaxine Metabolic pathways". SMPBD. Retrieved February 3, 2022.
^ abcdefg"Desvenlafaxine Succinate Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Retrieved 18 March 2019.
^ ab"Withdrawal Assessment Report for Dessvenlafaxime" (PDF). EMA. p. 3. Retrieved 22 March 2019.
^Cite error: The named reference :0 was invoked but never defined (see the help page).
^"Desvenlafaxine Pregnancy and Breastfeeding Warnings". Drugs.com. Retrieved 19 March 2019.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Desvenlafaxine - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat depression. It is an antidepressant of the serotonin-norepinephrine...
Toludesvenlafaxine is described as an SNDRI and prodrug to desvenlafaxine. However, unlike desvenlafaxine, which has in vitro IC50Tooltip half-maximal inhibitory...
is extensively metabolized in the liver via the CYP2D6 isoenzyme to desvenlafaxine (O-desmethylvenlafaxine, now marketed as a separate medication named...
CE, Johnston G, Bray J, Shah S, Abou-Gharbia M, Andree TH (2006). "Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor". J...
(Pimozide) – a typical antipsychotic used to treat tic disorder Pristiq (desvenlafaxine) – an antidepressant of the SNRI class Prolixin (fluphenazine) – typical...
Pharmaceutical, Inc. announced Paragraph IV ANDA litigation with Pfizer on Desvenlafaxine (Pristiq™). Alembic also entered into a product development and licence...
antidepressant treatment. The antidepressants included in the study were desvenlafaxine, escitalopram, fluoxetine, paroxetine, sertraline, and venlafaxine....
described as SNRIs, duloxetine (Cymbalta), venlafaxine (Effexor), and desvenlafaxine (Pristiq) are in fact relatively selective as serotonin reuptake inhibitors...
incidence of insomnia of all second-generation antidepressants, apart from desvenlafaxine. It is also associated with about 20% increased risk of headache. Bupropion...
The molecular formula C16H25NO2 may refer to: Dendrobine Desvenlafaxine Emixustat Hydroxy alpha sanshool Pentethylcyclanone Tramadol This set index page...
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