The dermoepidermal junction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which consist of type VII collagen.[1][2]
^"Dermo-epidermal junction zone". Netzwerk Epidermolysis bullosa. 2006. Archived from the original on 11 February 2013. Retrieved 30 November 2011.
^Standring S, ed. (2016). "Skin and its appendages". Gray's Anatomy: The Anatomical Basis of Clinical Practice (41 ed.). Elsevier. p. 147. ISBN 978-0-7020-5230-9.
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The dermoepidermaljunction or dermal-epidermal junction (DEJ) is the interface between the epidermal and the dermal layers of the skin. The basal cells...
DEJ may stand for: Dermoepidermaljunction, the interface between the dermis and the epidermis inside the skin Dentinoenamel junction, the interface between...
cytoplasm with coarse granules. They are usually located at the dermoepidermaljunction or in the dermis of the skin. Dermal nevus cells can be further...
melanoma is continuous proliferation of atypical melanocytes at the dermoepidermaljunction. Other histological signs of acral lentiginous melanoma include...
release material from their nuclei. This material diffuses to the dermoepidermaljunction, where it binds to circulating antibodies, thereby leading to a...
Anchoring fibrils are essential to the functional integrity of the dermoepidermaljunction. Epidermolysis bullosa dystrophica, also known as Dystrophic EB...
hydropic degeneration) is a dermatitis with vacuolization at the dermoepidermaljunction, with lymphocytic inflammation at the epidermis and dermis. An...
VII collagen within anchoring fibril structures located at the dermoepidermaljunction in skin. Damaged skin may become infected. Diagnosis is by observing...
Unclear events subsequently result in a separation along the dermoepidermaljunction and eventually stretch bullae.[citation needed] Diagnosis consist...
granulosum, rete ridge elongation, and large blood vessels at the dermoepidermaljunction.[citation needed] On dermatoscopic examination, warts will commonly...
interface dermatitis": Mild inflammatory cell infiltrate along the dermoepidermaljunction (black arrow in image) Vacuolization within the basal keratinocytes...
distinction. Histopathologically, there is inflammation at the dermoepidermaljunction and degeneration of the basal cell layer. Unlike in SLE, an anti-nuclear...
an epithelioid morphology. Apoptotic cells may be seen at the dermoepidermaljunction. The main histologic differential diagnoses are pigmented spindle...
fibers. The thinnest, or oxytalan fibers, are perpendicular to the dermoepidermaljunction and are the most superficial. In this work, electron microscopy...
specificity and sensitivity. The antibody also reacts positively against junctional nevus cells but not intradermal nevi, and against fetal melanocytes but...
(oxytalan fibers) are very thin and directed perpendicularly to the dermoepidermaljunction. They start from a plexus with the tinctorial characteristics of...
cells of epidermis to the basal lamina and hence to dermis) of the dermoepidermaljunction[further explanation needed], leading to blister formation as loss...
areas below the epidermis (subepidermal), as well as along the dermoepidermaljunction (area that joins the epidermis and dermis), suggests paraneoplastic...
Bethlem myopathy, atopic dermatitis VII Forms anchoring fibrils in dermoepidermaljunctions COL7A1 Epidermolysis bullosa dystrophica VIII Some endothelial...
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