Paraneoplastic pemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor. It is hypothesized that antigens associated with the tumor trigger an immune response resulting in blistering of the skin and mucous membranes.
While patients with malignant and benign tumors are both at risk, malignancy is associated with high mortality rates (near 90%). Current treatment focuses on general wound healing and administering corticosteroids, which has not demonstrated a high success rate. Recent research developments aim to treat the underlying tumor in order to alleviate the symptoms of PNP.
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Paraneoplasticpemphigus (PNP) is an autoimmune disorder stemming from an underlying tumor. It is hypothesized that antigens associated with the tumor...
several types of pemphigus (pemphigus vulgaris, pemphigus foliaceus, intraepidermal neutrophilic IgA dermatosis, and paraneoplasticpemphigus) vary in severity...
paraneoplastic syndromes may vary greatly. For example, paraneoplasticpemphigus often included infection as a major cause of death. Paraneoplastic pemphigus...
injury; striate palmoplantar keratoderma, Carvajal syndrome and paraneoplasticpemphigus. Desmoplakin exists as two predominant isoforms; the first, known...
Olivry, Thierry (2020-11-23). "Deep pemphigus (pemphigus vulgaris, pemphigus vegetans and paraneoplasticpemphigus) in dogs, cats and horses: a comprehensive...
most common cause of paraneoplasticpemphigus in adults. Castleman's disease is the most common cause of paraneoplasticpemphigus in children. List of...
Pemphigus vegetans of Hallopeau represents a mild form of pemphigus vegetans. Pemphigus vegetans of Neumann represents a severe form of pemphigus vegetans...
immunofluorescence when using salt-split skin include: For several subtypes of pemphigus a variety of substrates are used for indirect immunofluorescence: List...
antigen recognized by autoantibodies in the autoimmune disease paraneoplasticpemphigus (PNP). Alternative splicing results in multiple transcript variants...
expressed in the human integumentary system List of target antigens in pemphigus List of immunofluorescence findings for autoimmune bullous conditions...
are uncommon in UCD. UCD is associated with increased risk of paraneoplasticpemphigus as well as bronchiolitis obliterans (BO), AA amyloidosis, vascular...
Polycythemia may occur due to increased erythropoietin production as part of a paraneoplastic syndrome. The word is from leio- + myo- + -oma, 'smooth-muscle tumor'...
receptor antibodies Reference ranges for blood tests#Autoantibodies Paraneoplastic syndrome Böhm I. Apoptosis: the link between autoantibodies and leuko-/lymphocytopenia...
PMID 26025581. Melchionda, V.; Harman, K. E. (2019-08-04). "Pemphigus vulgaris and pemphigus foliaceus: an overview of the clinical presentation, investigations...
poisoning and overdose Mushroom poisoning Plasmapheresis II Other III Paraneoplastic syndrome Neurologic Plasmapheresis or immunoadsorption III Pancreatitis...
form must be differentiated from similar appearing conditions such as pemphigus vulgaris, bullous pemphigoid, mycosis fungoides, and lupus erythematosus...
Firm to the touch Growing Metastatic melanoma may cause nonspecific paraneoplastic symptoms, including loss of appetite, nausea, vomiting, and fatigue...
cyclic hydrocarbons and Agent Orange.[citation needed] It can be a paraneoplastic phenomenon. Alcohol Estrogen Iron Hepatitis C virus Porphyria cutanea...
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