Autoimmune disease of skin and connective tissue characterized by large blisters
Medical condition
Bullous pemphigoid
A patient present with legs covered in popped blisters caused by bullous pemphigoid. The blisters cover his entire body.
Specialty
Dermatology
Bullous pemphigoid (a type of pemphigoid) is an autoimmune pruritic skin disease that typically occurs in people aged over 60, that may involve the formation of blisters (bullae) in the space between the epidermal and dermal skin layers. It is classified as a type II hypersensitivity reaction, which involves formation of anti-hemidesmosome antibodies, causing a loss of keratinocytes to basement membrane adhesion.
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Bullouspemphigoid (a type of pemphigoid) is an autoimmune pruritic skin disease that typically occurs in people aged over 60, that may involve the formation...
gestationis Bullouspemphigoid (BP) Mucous membrane pemphigoid (MMP); also called cicatricial pemphigoidBullous and mucous membrane pemphigoid usually affect...
present in pemphigus and mucous membrane pemphigoid, but not in bullouspemphigoid. In mucous membrane pemphigoid, the autoimmune reaction occurs in the...
indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullouspemphigoid-like appearance. This disease can often be difficult to treat even...
Gestational pemphigoid (GP) is a rare autoimmune variant of the skin disease bullouspemphigoid, and first appears in pregnancy. It presents with tense...
impetigo Impetigo on the back of the neck A severe case of facial impetigo Bullous impetigo, mainly seen in children younger than two years, involves painless...
Dystonin (DST), also known as bullouspemphigoid antigen 1 (BPAG1), isoforms 1/2/3/4/5/8, is a protein that in humans is encoded by the DST gene. This...
keratinocytes, seen in diseases such as pemphigus vulgaris. It is absent in bullouspemphigoid, making it useful for differential diagnosis. This histological feature...
Luca; Amber, Kyle T. (2022-07-07). "Insights Into the Pathogenesis of BullousPemphigoid: The Role of Complement-Independent Mechanisms". Frontiers in Immunology...
bites and other blistering conditions such as bullouspemphigoid, linear IgA bullous dermatosis, and bullous systemic lupus erythematosus. The diagnosis...
dyshidrosis. Other, much rarer conditions that cause blisters include: Bullouspemphigoid: a skin disease that causes large, tightly filled blisters to develop...
bandaging, wound management, and pain management. BullouspemphigoidBullouspemphigoid is an autoimmune bullous disease that mainly affects older individuals...
decline and he developed a rare and horrible skin disease called bullouspemphigoid. He also became very depressed. That, along with the many medications...
other NSAIDs, ibuprofen has been associated with the onset of bullouspemphigoid or pemphigoid-like blistering. As with other NSAIDs, ibuprofen has been reported...
Vesicular pemphigoid is a cutaneous condition, a clinical variant of bullouspemphigoid, characterized by a dermatitis herpetiformis-like presentation...
investigated for many additional disorders, including treatment of bullouspemphigoid nonmelanoma skin cancers. Niacinamide may be beneficial in treating...
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