Discoid lupus erythematosus lesion on the face of musician Seal.
Specialty
Dermatology, Immunology
Discoid lupus erythematosus is the most common type of chronic cutaneous lupus (CCLE), an autoimmune skin condition on the lupus erythematosus spectrum of illnesses.[1][2] It presents with red, painful, inflamed and coin-shaped patches of skin with a scaly and crusty appearance, most often on the scalp, cheeks, and ears. Hair loss may occur if the lesions are on the scalp.[3] The lesions can then develop severe scarring, and the centre areas may appear lighter in color with a rim darker than the normal skin.[3] These lesions can last for years without treatment.[4]
Patients with systemic lupus erythematous develop discoid lupus lesions with some frequency.[4] However, patients who present initially with discoid lupus infrequently develop systemic lupus.[3] Discoid lupus can be divided into localized, generalized, and childhood discoid lupus.[3]
The lesions are diagnosed by biopsy.[5] Patients are first treated with sunscreen and topical steroids.[5] If this does not work, an oral medication—most likely hydroxychloroquine or a related medication—can be tried.[5]
^"Cutaneous Lupus Erythematosus | American Skin Association". www.americanskin.org. Retrieved 2018-12-11.
^Wollina, Uwe; Hansel, Gesina; Koch, André; Abdel-Naser, Mohamed Badawy (2006). "Topical pimecrolimus for skin disease other than atopic dermatitis". Expert Opinion on Pharmacotherapy. 7 (14): 1967–1975. doi:10.1517/14656566.7.14.1967. PMID 17020422. S2CID 44901447.
^ abcdJames, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.) Saunders. Chapter 8. ISBN 0-7216-2921-0.
^ abCite error: The named reference :2 was invoked but never defined (see the help page).
^ abcCite error: The named reference :1 was invoked but never defined (see the help page).
and 26 Related for: Discoid lupus erythematosus information
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