Vacuolar interface dermatitis, with lymphocytes in the dermis and epidermis (black arrow indicates one), and vacuolization (white arrow) at the dermoepidermal junction.Micrograph of a vacuolar interface dermatitis with dermal mucin, as may be seen in lupus. H&E stain.
Vacuolar interface dermatitis (VAC, also known as liquefaction degeneration, vacuolar alteration or hydropic degeneration) is a dermatitis with vacuolization at the dermoepidermal junction, with lymphocytic inflammation at the epidermis and dermis.[1]
^Bolognia, Jean L.; et al. (2007). Dermatology. St. Louis: Mosby. p. 11. ISBN 1-4160-2999-0.
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