positive regulation of cyclin-dependent protein serine/threonine kinase activity
transcription elongation from RNA polymerase II promoter
regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
transcription by RNA polymerase II
negative regulation by host of viral genome replication
positive regulation of transcription by RNA polymerase II
cell division
cell cycle
protein phosphorylation
transcription, DNA-templated
snRNA transcription by RNA polymerase II
positive regulation of phosphorylation of RNA polymerase II C-terminal domain
regulation of transcription by RNA polymerase II
positive regulation of DNA-templated transcription, elongation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
8812
12454
Ensembl
ENSG00000090061
ENSMUSG00000021258
UniProt
O75909
O88874 Q3U3M5
RefSeq (mRNA)
NM_001099402 NM_003858
NM_009832
RefSeq (protein)
NP_001092872
NP_033962
Location (UCSC)
Chr 14: 99.48 – 99.54 Mb
Chr 12: 108.15 – 108.17 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Cyclin-K is a protein that in humans is encoded by the CCNK gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000090061 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021258 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Cite error: The named reference Edwards_1998 was invoked but never defined (see the help page).
^Fu TJ, Peng J, Lee G, Price DH, Flores O (December 1999). "Cyclin K functions as a CDK9 regulatory subunit and participates in RNA polymerase II transcription". The Journal of Biological Chemistry. 274 (49): 34527–30. doi:10.1074/jbc.274.49.34527. PMID 10574912.
Cyclin-K is a protein that in humans is encoded by the CCNK gene. The protein encoded by this gene is a member of the transcription cyclin family. These...
Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). Cyclins were originally...
Cyclin D1 is a protein that in humans is encoded by the CCND1 gene. The CCND1 gene encodes the cyclin D1 protein. The human CCND1 gene is located on the...
Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk...
Cyclin D is a member of the cyclin protein family that is involved in regulating cell cycle progression. The synthesis of cyclin D is initiated during...
screening revealed structurally diverse molecular glue degraders targeting cyclinK. The discovery that manumycin polyketides acted as molecular glues, fostering...
Cyclin E is a member of the cyclin family. Cyclin E binds to G1 phase Cdk2, which is required for the transition from G1 to S phase of the cell cycle...
Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, et al. (October 2003). "Targets of the cyclin-dependent kinase Cdk1". Nature. 425 (6960): 859–864...
Cyclin A is a member of the cyclin family, a group of proteins that function in regulating progression through the cell cycle. The stages that a cell passes...
Cyclin-A2 is a protein that in humans is encoded by the CCNA2 gene. It is one of the two types of cyclin A: cyclin A1 is expressed during meiosis and embryogenesis...
G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. Cyclin B1 is a regulatory protein involved in mitosis. The gene...
G1/S-specific cyclin-D3 is a protein that in humans is encoded by the CCND3 gene. The protein encoded by this gene belongs to the highly conserved cyclin family...
G1/S-specific cyclin-E1 is a protein that in humans is encoded by the CCNE1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family...
(alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that...
largely determined by the activation of cyclin-dependent kinases by regulatory protein subunits called cyclins, different forms of which are produced at...
threshold level of active cyclin-B1/CDK1 complex, also known as cyclin-B1/Cdc2 or the maturation promoting factor (MPF). Active cyclin-B1/CDK1 triggers irreversible...
Cyclin-T1 is a protein that in humans is encoded by the CCNT1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose...
G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene. The protein encoded by this gene belongs to the highly conserved cyclin family...
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. It is ubiquitously expressed...
family of cyclin dependent kinase (Cdk) inhibitor proteins. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes...
Global Information
