Condition that serves as a reason not to take a certain medical treatment
In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient.[1][2] Contraindication is the opposite of indication, which is a reason to use a certain treatment.
Absolute contraindications are contraindications for which there are no reasonable circumstances for undertaking a course of action (that is, overriding the prohibition). For example:
Children and teenagers with viral infections should not be given aspirin because of the risk of Reye syndrome.[3]
A person with an anaphylactic food allergy should never eat the food to which they are allergic.
A person with hemochromatosis should not be administered iron preparations.
Some medications are so teratogenic that they are absolutely contraindicated in pregnancy; examples include thalidomide and isotretinoin.
Relative contraindications are contraindications for circumstances in which the patient is at higher risk of complications from treatment, but these risks may be outweighed by other considerations or mitigated by other measures. For example, a pregnant person should normally avoid getting X-rays, but the risk from radiography may be outweighed by the benefit of diagnosing (and then treating) a serious condition such as tuberculosis.
Another principal pair of terms for relative contraindications versus absolute contraindications is cautions versus contraindications, or (similarly) precautions versus contraindications: these pairs of terms are respectively synonymous. Which pair is used depends on nomenclature enforced by each organization's style. For example, the British National Formulary uses the cautions versus contraindications pair, and various U.S. CDC webpages use precautions versus contraindications. The logic of the latter two styles is the idea that readers must never be confused: the word contraindication in that usage always is meant in its absolute sense, providing unmistakable word-sense disambiguation.
^"Contraindication - Medical Definition and More from Merriam-Webster". Archived from the original on 3 October 2011. Retrieved 14 December 2010.
^Vorvick, Linda J., MD (21 January 2013). A.D.A.M. Health Solutions, Ebix Inc.; David Zieve; MHA, David; R. Eltz; Stephanie Slon; Nissi Wang (eds.). "Contraindication: MedlinePlus Medical Encyclopedia". MEDLINE. United States National Library of Medicine. Archived from the original on 5 July 2016. Retrieved 7 November 2014.{{cite web}}: CS1 maint: multiple names: authors list (link)
^Raymond S. Sinatra; Jonathan S. Jahr; J. Michael Watkins-Pitchford (2011). The Essence of Analgesia and Analgesics. Cambridge University Press. p. 253. ISBN 978-0-521-14450-6.
patient. Contraindication is the opposite of indication, which is a reason to use a certain treatment. Absolute contraindications are contraindications for...
Contraindications to breastfeeding are those conditions that could compromise the health of the infant if breast milk from their mother is consumed. Examples...
Methamphetamine (contracted from N-methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and...
Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems. Guidelines recommend...
positive CST indicates high risk of fetal death due to hypoxia and is a contraindication to labor. Patient's obstetricians usually consider operative delivery...
Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma)...
Rasburicase (trade names Elitek in the US and Fasturtec in the EU) is a medication that helps to clear uric acid from the blood. It is a recombinant version...
Metoclopramide is a medication used for stomach and esophageal problems. It is commonly used to treat and prevent nausea and vomiting, to help with emptying...
Ranitidine, previously sold under the brand name Zantac among others, is a medication used to decrease stomach acid production. It was commonly used in...
Domperidone, sold under the brand name Motilium among others, is a dopamine antagonist medication which is used to treat nausea and vomiting and certain...
peanuts was noted for the inhaler as a contraindication but now is not. It has never been a contraindication when administered as a nebulized solution...
Metamizole or dipyrone is a painkiller, spasm reliever, and fever reliever drug. It is most commonly given by mouth or by intravenous infusion. It belongs...
perhaps even 6 hours) of ischaemic stroke onset when there are no contraindications to treatment. Massive pulmonary embolism. For the treatment of a massive...
Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention...
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin...
or younger. Preexisting eye disorders such as uveitis are another contraindication. Although PIOLs for hyperopia are being investigated, there is less...
when tropicamide alone is not sufficient. Narrow-angle glaucoma is a contraindication to phenylephrine use. As a mydriatic, it is available in 2.5% and 10%...
Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain...
in children younger than two years old. In the European Union, the contraindication applies to children under 12 years of age.[medical citation needed]...
Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic...
Atropine is a tropane alkaloid and anticholinergic medication used to treat certain types of nerve agent and pesticide poisonings as well as some types...
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. It is used to treat anxiety (including anxiety disorders), trouble...
Dulaglutide, sold under the brand name Trulicity among others, is a medication used for the treatment of type 2 diabetes in combination with diet and exercise...
Tesamorelin (INN) (trade name Egrifta SV) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated...
Haloperidol, sold under the brand name Haldol among others, is a typical antipsychotic medication. Haloperidol is used in the treatment of schizophrenia...
The upright row is a weight training exercise performed by holding a weight with an overhand grip and lifting it straight up to the collarbone. This is...
Chlortetracycline (trade name Aureomycin, Lederle Laboratories) is a tetracycline antibiotic, the first tetracycline to be identified. It was discovered...
Barbiturates are a class of depressant drugs that are chemically derived from barbituric acid. They are effective when used medically as anxiolytics, hypnotics...
by default, the Food and Drug Administration (FDA) has introduced contraindication guidelines in regard to hydroxyzine. Use by those at risk for or showing...
Global Information