Plasma membrane invagination at the cell division site
In this electron micrograph of a cell, the cleavage furrow has nearly completely divided the cell.Cilliate undergoing the last processes of binary fission, with the cleavage furrow being clearly visible.
In cell biology, the cleavage furrow is the indentation of the cell's surface that begins the progression of cleavage, by which animal and some algal cells undergo cytokinesis, the final splitting of the membrane, in the process of cell division. The same proteins responsible for muscle contraction, actin and myosin, begin the process of forming the cleavage furrow, creating an actomyosin ring. Other cytoskeletal proteins and actin binding proteins are involved in the procedure.
In cell biology, the cleavagefurrow is the indentation of the cell's surface that begins the progression of cleavage, by which animal and some algal cells...
synthesized pre-messenger RNA (mRNA) Cleavagefurrow, in cell biology, the indentation that begins the process of cleavage, by which animal cells undergo cytokinesis...
forming a cleavagefurrow without the central spindle, whereas in both C. elegans embryos and human tissue culture cells a cleavagefurrow is observed...
been traced back to the very first cleavagefurrow. It was demonstrated in the frog embryo that the first cleavagefurrow widens in the animal hemisphere...
spindle is important for setting up the cleavagefurrow position, for bringing myosin to the cleavagefurrow, and for driving basal myosin clearing. Actomyosin-based...
in green algae occurs via a diverse range of mechanisms, including cleavagefurrows in some algae and cell plates in others. Plants (=Chloroplastida) of...
propagating cell division along the surface, assists in deepening the cleavagefurrow, and finally heals the membrane after separation of blastomeres. The...
origin of the blastocoel in Xenopus has been shown to be from the first cleavagefurrow, which is widened and sealed with tight junctions to create a cavity...
phosphorylated GFAP, and a movement of this modified protein to the cleavagefurrow. There are different sets of kinases at work; cdc2 kinase acts only...
process necessary for completing cell division. In animal cells, a cleavagefurrow (pinch) containing a contractile ring, develops where the metaphase...
leading to adhesion formation. In animals, the ring forms along the cleavagefurrow on the inside of the plasma membrane then splits by abscission. In...
force created by the spindle poles to allow the chromosomes to move, cleavagefurrow management and distance segregation. Germ cells Gametes Gametocytogenesis...
chromatids in anaphase. This causes the chromatin to be trapped in the cleavagefurrow and form 4N G1 cells due to cytokinesis failure. This enzyme enhances...
1247/csf.26.529. PMID 11942606. Fang, X (2010). "Biphasic targeting and cleavagefurrow ingression directed by the tail of a myosin-II". J Cell Biol. 191 (7):...
Umeda, M (1996). "Redistribution of phosphatidylethanolamine at the cleavagefurrow of dividing cells during cytokinesis". Proceedings of the National...
cyclins. Telophase is the last stage of the cell cycle in which a cleavagefurrow splits the cells cytoplasm (cytokinesis) and chromatin. This occurs...
spindle, a spindle midzone, and a central spindle complex. Because cleavagefurrow ingression is primarily triggered by signals from the spindle midzone...
struggle for extra chromosomes. This competition causes disarrayment in cleavagefurrow formation and the normal consequence is death of the zygote. Only two...
light chain at the cleavagefurrow. Inhibition of Aurora B activity prevents proper myosin II localization to the cleavagefurrow and disrupts spindle...
pre-fertilization cortical granule exocytotic events occur in the cell's cleavagefurrow simultaneously with polar body formation. An assortment of hypotheses...
Porter ME, Pollard TD (Oct 1978). "Alpha-actinin localization in the cleavagefurrow during cytokinesis". The Journal of Cell Biology. 79 (1): 268–275....
further research that found anillin in high concentrations near the cleavagefurrow coinciding with RhoA, a key regulator of contractile ring formation...
Simanis V, Lasky LA (August 1997). "PSTPIP: a tyrosine phosphorylated cleavagefurrow-associated protein that is a substrate for a PEST tyrosine phosphatase"...
at the cleavagefurrow in early telophase, accumulated in the middle of the intercellular bridge with full ingression of the cleavagefurrow in mid telophase...