54 °C (129 °F; 327 K) (single enantiomer); 67 °C (racemic mixture)
Boiling point
467.2 °C (873.0 °F; 740.3 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
Cicutoxin is a naturally-occurring poisonous chemical compound produced by several plants from the family Apiaceae including water hemlock (Cicuta species) and water dropwort (Oenanthe crocata).[1] The compound contains polyene, polyyne, and alcohol functional groups and is a structural isomer of oenanthotoxin, also found in water dropwort. Both of these belong to the C17-polyacetylenes chemical class.[2]
It causes death by respiratory paralysis resulting from disruption of the central nervous system.[2] It is a potent, noncompetitive antagonist of the gamma-aminobutyric acid (GABA) receptor. In humans, cicutoxin rapidly produces symptoms of nausea, emesis and abdominal pain, typically within 60 minutes of ingestion. This can lead to tremors, seizures, and death.[1] LD50(mouse; i.p.) ~9 mg/kg[3]
^ abCite error: The named reference Schep was invoked but never defined (see the help page).
^ abCite error: The named reference Gung was invoked but never defined (see the help page).
^Wink, Michael; Van Wyk, Ben-Erik (2008). Mind-Altering and Poisonous Plants of the World. Portland: Timber Press. p. 87. ISBN 9780881929522.
Cicutoxin is a naturally-occurring poisonous chemical compound produced by several plants from the family Apiaceae including water hemlock (Cicuta species)...
poisonous to humans. Three members of the genus contain a toxin named cicutoxin which causes central nervous system stimulatory effects including seizures...
Musquash-poison. The plant contains cicutoxin, which disrupts the workings of the central nervous system. In humans, cicutoxin rapidly produces symptoms of nausea...
structurally closely related to the toxins cicutoxin and carotatoxin. Oenanthotoxin is a C17 polyacetylene isomer of cicutoxin. Oenanthotoxin concentration in plants...
is its toxicity. Cicutoxin is the toxin that is produced, making water hemlock the most poisonous plant in North America. Cicutoxin is a yellowish liquid...
the plant causing death in as little as 15 minutes. The chief poison is cicutoxin, an unsaturated aliphatic alcohol that is most concentrated in the roots...
barbiturates, alcohol (ethanol), inhaled anaesthetics, kavalactones, cicutoxin, and picrotoxin, among others. Much like the GABAA receptor, the GABAB...
other members of the Asteraceae and Apiaceae families). Some examples are cicutoxin, oenanthotoxin, and falcarinol. These compounds are highly bioactive,...
are cows or other grazing animals. If a dog does ingest hemlock, the cicutoxin in the plant can be fatal very quickly as it causes the heart and nervous...
bend in the molecule. It is structurally related to oenanthotoxin and cicutoxin. Falcarinol is an intense irritant that can cause allergic reactions and...
freshly pulled out of the ground, is extremely poisonous and contains cicutoxin, a central nervous system stimulant that induces seizures.[citation needed]...
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