Ceramide synthase 3 information

CERS3
Identifiers
Aliases	CERS3, ARCI9, LASS3, ceramide synthase 3
External IDs	OMIM: 615276 MGI: 2681008 HomoloGene: 18719 GeneCards: CERS3
Gene location (Human)
Chr.	Chromosome 15 (human)
End	100,544,995 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	66,473,439 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; gums; ; oral cavity; ; vulva; ; human penis; ; vagina; ; thymus; ; nipple; ; palpebral conjunctiva; ; amniotic fluid;
	Top expressed in
	spermatocyte; ; esophagus; ; seminiferous tubule; ; spermatid; ; conjunctival fornix; ; skin of back; ; skin of abdomen; ; lip; ; epidermis; ; cornea;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; DNA binding; sphingosine N-acyltransferase activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	integral component of membrane; nuclear membrane; endoplasmic reticulum membrane; nucleus; membrane; endoplasmic reticulum;
Biological process	ceramide biosynthetic process; sphingolipid biosynthetic process; keratinocyte differentiation; lipid metabolism; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	204219
	545975
	ENSG00000154227
	ENSMUSG00000030510
	Q8IU89
	Q1A3B0
	NM_001290341; NM_001290342; NM_001290343; NM_178842; NM_001378789
	NM_001164201
	NP_001277270; NP_001277271; NP_001277272; NP_849164; NP_001365718
	NP_001157673
	Wikidata
View/Edit Human	View/Edit Mouse

Ceramide synthase 3 (CersS3), also known as longevity assurance homologue 3, is an enzyme that is encoded in humans by the CERS3 gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000154227 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030510 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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