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Lactosylceramide information


The structure of lactosylceramide.

The Lactosylceramides, also known as LacCer, are a class of glycosphingolipids composed of a variable hydrophobic ceramide lipid and a hydrophilic sugar moiety. Lactosylceramides are found in microdomains on the plasma layers of numerous cells. Moreover, they are a type of ceramide including lactose, which is an example of a globoside.

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Lactosylceramide

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The Lactosylceramides, also known as LacCer, are a class of glycosphingolipids composed of a variable hydrophobic ceramide lipid and a hydrophilic sugar...

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CDw17 antigen

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CDw17 antigen is a lactosylceramide, a class of glycosphingolipids found in microdomains on the plasma layers of numerous cells. It is found on human neutrophils...

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Globotriaosylceramide

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is not a protein. It is formed by the alpha linkage of galactose to lactosylceramide catalyzed by A4GALT. It is metabolized by alpha-galactosidase, which...

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Glycosphingolipid

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group. The structural similarity of most glycolipids is the so-called lactosylceramide, that is, a lactose disaccharide that is glycosidically bound to a...

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Cerebroside

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linked glycosidically to the C-1 hydroxyl group of ceramide, such as in lactosylceramide. Cerebrosides containing a sulfuric ester (sulfate) group, known as...

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Galactosylceramidase

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galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. It is a lysosomal protein, encoded...

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Sialyltransferase

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alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8); lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9). These enzymes use a nucleotide...

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NADPH oxidase

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platelet-derived growth factor (PDGF), tumor necrosis factor (TNFa), lactosylceramide, interleukin-1, and oxidized LDL. It is also stimulated by agonists...

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ST3GAL5

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Lactosylceramide alpha-2,3-sialyltransferase is an enzyme that in humans is encoded by the ST3GAL5 gene. Ganglioside GM3 is known to participate in the...

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GLTP

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complexed with 8:0 Lactosylceramide 2evd: Crystal structure of human Glycolipid Transfer Protein complexed with 12:0 Lactosylceramide 2evl: Crystal structure...

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A4GALT

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Lactosylceramide 4-alpha-galactosyltransferase is an enzyme that in humans is encoded by the A4GALT gene. The protein encoded by this gene catalyzes the...

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B4GALT5

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poly-N-acetyllactosamine biosynthetic process ganglioside biosynthetic process via lactosylceramide central nervous system neuron axonogenesis central nervous system myelination...

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